The figure adapted from Anbazhakan et al. represents imaging (black and white), hemodynamic forces (magenta), and collateral artery tracing (cyan) in a cohesive collage. The use of a collage symbolizes the interdisciplinary nature of this work.

See Anbazhakan et al. and News & Views by Mayerich and Wythe

The cover image features original ECG traces from the STORM mice, in which ventricular tachycardia occurs owing to hypokalemia and acute myocardial infarction. Using this new model of non-genetic, spontaneous arrhythmia, Grune et al. show that leukocytes regulate the arrhythmia burden, and that immune cell dysfunction elicits an electrical storm and sudden cardiac death.

See Grune et al. and News & Views by Nicolás-Ávila and Hidalgo

Thalidomide treatment of individuals with severely symptomatic arteriovenous malformations who are refractory to conventional therapies holds promise, shows study by Boon et al.

See Boon et al.and News & Views by Teng and Siegel

Stem cells (green) and blood vessels (red) in early stage mouse intestinal adenoma.

See Bernier-Latmani et al. and News & Views by Koh

Popescu et al. develop a deep learning approach that combines neural networks and survival analysis from cardiac magnetic resonance images and clinical covariates for patients with ischemic heart disease to predict arrhythmic sudden death.

See Popescu et al. and News & Views by Krittanawong

Koenig et al. present a comprehensive cellular atlas of healthy and failing human hearts, based on single-cell and single-nucleus RNA sequencing of cardiac biopsies from 45 individuals.

See Koenig et al.

Spielmann et al. screen the cardiac function and structure of about 4,000 monogenic knockout mice to identify 486 new genes whose lack results in cardiac disease, and validate a number of these genes in humans via UK Biobank human data.

See Spielmann et al. and News & Views by Ahlberg and Olesen

The cover image of our first issue is a wool artwork entitled ‘Reach’, created by contemporary British artist Sarah Vaci. Reflecting the originality and courage of the artwork, Nature Cardiovascular Research aims to bring together the cardiovascular and blood community, and promote, champion and disseminate inspiring, thought-provoking and original research.