Aims & Scope

Cancer is a devastating disease that causes one in six deaths globally. A large proportion of these deaths could be prevented, but improving prevention and treatment outcomes requires accurate diagnosis, the development of effective and precise treatment modalities and a better understanding of the socioeconomic factors that affect cancer incidence, prevalence and mortality. 

Nature Cancer aims to provide a unique forum through which the cancer community will learn about the latest, most significant cancer-related advances across the life, physical, applied and social sciences. Areas of interest include fundamental, preclinical research that furthers our understanding of the mechanisms underlying tumour initiation, propagation and progression; work aiming to translate this knowledge to the clinic by focusing on new approaches for the development and delivery of diagnostic and therapeutic modalities; clinical studies informing cancer diagnosis, treatment and prevention; and new ways of understanding the global societal impact of cancer.

In addition to publishing original research, Nature Cancer will publish Comments, Reviews, News & Views, Features and Correspondence of high significance across the range of disciplines relating to cancer research.


Topics covered in the journal include:


Cancer biology, encompassing oncogenic and tumour-suppressive mechanisms that deregulate molecular pathways and cellular processes, including tumour-initiating cells/cancer stem cells

• Cancer genetics and genomics, including functional genomics and the mechanisms underlying genome integrity, genomic instability and mutation

Tumour evolution and heterogeneity

Tumour–host interactions, including the tumour microenvironment (molecular, cellular, physical) and systemic effects

Tumour immunology and immunotherapy

Metastasis, including mechanisms of cancer cell dissemination, seeding, dormancy and growth in secondary sites

Therapy, including design and delivery, targeted, combination and precision therapy and the study of therapy resistance

Clinical work that informs cancer diagnosis, treatment and prevention 

• Cancer models and methodology to investigate, diagnose and treat cancer

Systems biology, including large-scale and single-cell omics and multi-omics approaches to characterise and study cancer

Social, ethical and policy issues relating to cancer research, prevention, diagnosis and treatment