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Volume 4 Issue 7, 1 July 2020

Multimodal nanoparticles for cancer theranostics

This issue highlights the stabilization of a brain–computer interface via the alignment of neural activity, nanoprobes for cancer theranostics, the enhancement of the performance of nanomedicines via the forced clearance of erythrocytes, tumour-targeted nanoparticles for the combination of tumour-infarction therapy and chemotherapy, and tumour-cell-derived microvesicles for relieving biliary obstruction in patients with extrahepatic cholangiocarcinoma.

The cover illustrates renally clearable gold–protein nanoparticles displaying multicolour fluorescence for use in the detection, resection and treatment of breast cancer in mice.

See Yang, J. et al.

Image: Roscoe Lamontagne, Roscoe Studio. Cover design: Alex Wing.

Editorial

  • Two recent high-profile retractions of COVID-19 papers exemplify that trust cannot be taken for granted. To strengthen it, scientific review will have to become more transparent.

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  • In the presence of recording instabilities, the performance of brain–computer interfaces can be robustly maintained by exploiting ‘hidden’ structures underlying neural activity.

    • Lahiru N. Wimalasena
    • Lee E. Miller
    • Chethan Pandarinath
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  • Gold nanoclusters stabilized by the milk metalloprotein α-lactalbumin and displaying multicolour and multimodal fluorescence aid the detection, resection and treatment of breast tumours in mice.

    • Gang He
    • Peng Huang
    • Xiaoyuan Chen
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