Volume 1 Issue 9 September 2017

Volume 1 Issue 9

Location-broadcasting chips

This issue highlights the design of localizable implantable magnetic microdevices, and also includes advances in cancer-cell detection via lasing, in tumour therapy with a non-toxic dendrimer, and in the amplification of rare DNA-sequence variants.

The cover illustrates the concept of implantable microdevices that broadcast their location when in a magnetic-field gradient by emitting a magnetic-field-dependent radiofrequency signal ( Article).

Image from Pixologicstudio/Getty images. Adapted by Karen Moore.

Editorial

News and Views

  • News and Views |

    Laser light emitted by fluorescently stained human tissue inside a laser cavity can be used to diagnose cancer.

    • Matjaž Humar
  • News and Views |

    Microchips embedding a magnetic sensor and a radiofrequency transmitter can be localized in the body of a mouse at submillimetre resolution when under a magnetic field.

    • Yong Lin Kong
    •  & Giovanni Traverso
  • News and Views |

    A dendrimer that depletes bioavailable copper as a result of its internal make-up displays powerful anticancer activity in mice, and no observable adverse effects.

    • Zhenbin Lyu
    •  & Ling Peng
  • News and Views |

    Causing nanoscale vibrations in bone-marrow stromal cells embedded in a soft collagen gel induces the cells to undergo osteogenic differentiation and mineralization via mechanosensitive signalling pathways.

    • Jeroen Eyckmans
    •  & Christopher S. Chen

Comment and Opinion

  • Comment |

    Interventional healthcare will evolve from an artisanal craft based on the individual experiences, preferences and traditions of physicians into a discipline that relies on objective decision-making on the basis of large-scale data from heterogeneous sources.

    • Lena Maier-Hein
    • , Swaroop S. Vedula
    • , Stefanie Speidel
    • , Nassir Navab
    • , Ron Kikinis
    • , Adrian Park
    • , Matthias Eisenmann
    • , Hubertus Feussner
    • , Germain Forestier
    • , Stamatia Giannarou
    • , Makoto Hashizume
    • , Darko Katic
    • , Hannes Kenngott
    • , Michael Kranzfelder
    • , Anand Malpani
    • , Keno März
    • , Thomas Neumuth
    • , Nicolas Padoy
    • , Carla Pugh
    • , Nicolai Schoch
    • , Danail Stoyanov
    • , Russell Taylor
    • , Martin Wagner
    • , Gregory D. Hager
    •  & Pierre Jannin

Reviews

Research