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Cancer & Aging Collection
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Progress towards the Sustainable Development Goals
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Partial reprogramming of the mammalian brain
Xu and colleagues used partial OSKM reprogramming in aged mice to drive cell-type proportions of the subventricular zone to more youthful levels, which equates to qualified rejuvenation of a neurogenic niche that is defined, in part, by restoration of neuroblast levels.
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Aging, longevity and age-related diseases
Our understanding of the biology of aging and longevity has grown tremendously over the past two decades.
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Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial
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Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy
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Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging
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Integration of polygenic and gut metagenomic risk prediction for common diseases