Volume 26 Issue 8, August 2021

WT1 regulates the differentiation of human neural progenitor cells (hNPCs). Human NPCs generated from embryonic stem cells were infected with control or WT1-shRNA lentivirus and then neuronal differentiation was induced. Lentivirus infected hNPCs (green) were labeled with neuronal marker, TUJ1 (red). The number of TUJ1+ neurons is decreased in WT1-shRNA infected hNPCs (bottom panel). For more information see the article by Fen Ji et al. on page 4221–4233.