Volume 24 Issue 2, February 2019

Chromosome 16p13.11 microduplication affects proliferation of patient-derived neuronal precursor cells. Cover image showing monolayer cultures of anterior neuronal precursor cells from an affected carrier of Chr16p13.11 microduplication (right panel) next to those from an unaffected non-carrier control subject (left panel) displaying characteristic rosette-like patterning showing uniform NESTIN expression (red) and mosaic OTX2 expression (green). The cells' nuclei are stained with DAPI (blue).

For more information on this topic, please refer to the article by Johnstone et al. on pages 294–311.