TABLE OF CONTENTS

Volume 23, Issue 1 (January 2018)

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Image

Metabolic mapping of downstream network activity following CNO-induced activation of hM3Dq in BNST VGAT neurons

C M Mazzone, D Pati, M Michaelides, J DiBerto, J H Fox, G Tipton, C Anderson, K Duffy, J M McKlveen, J A Hardaway, S T Magness, W A Falls, S E Hammack, Z A McElligott, Y L Hurd and T L Kash

Mol Psychiatry 23: 1; doi:10.1038/mp.2017.253

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News and Commentary

Preventive Treatment in Stress-Related Disorders

Countering posttraumatic LHPA activation in refugee mothers and their infants Open

E Ullmann, S R Bornstein, R S Lanzman, C Kirschbaum, S Sierau, M Doehnert, P Zimmermann, H Kindler, M Schauer, M Ruf-Leuschner, J M Fegert, K von Klitzing and U Ziegenhain

Mol Psychiatry 23: 2-5; advance online publication, November 14, 2017; doi:10.1038/mp.2017.235

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Perspectives

The iPSYCH2012 case–cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders Open

C B Pedersen, J Bybjerg-Grauholm, M G Pedersen, J Grove, E Agerbo, M Bækvad-Hansen, J B Poulsen, C S Hansen, J J McGrath, T D Als, J I Goldstein, B M Neale, M J Daly, D M Hougaard, O Mors, M Nordentoft, A D Børglum, T Werge and P B Mortensen

Mol Psychiatry 23: 6-14; advance online publication, September 19, 2017; doi:10.1038/mp.2017.196

Improved ethical guidance for the return of results from psychiatric genomics research

G Lázaro-Muñoz, M S Farrell, J J Crowley, D M Filmyer, R A Shaughnessy, R C Josiassen and P F Sullivan

Mol Psychiatry 23: 15-23; advance online publication, November 21, 2017; doi:10.1038/mp.2017.228

The perilous path from publication to practice

A M Chekroud and N Koutsouleris

Mol Psychiatry 23: 24-25; advance online publication, November 7, 2017; doi:10.1038/mp.2017.227

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Mechanisms of Drug Action

Engaging homeostatic plasticity to treat depression

E R Workman, F Niere and K F Raab-Graham

Mol Psychiatry 23: 26-35; advance online publication, November 14, 2017; doi:10.1038/mp.2017.225

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Expert Review

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry

T Notter, J M Coughlin, A Sawa and U Meyer

Mol Psychiatry 23: 36-47; advance online publication, December 5, 2017; doi:10.1038/mp.2017.232

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Reviews

Chemokines in depression in health and in inflammatory illness: a systematic review and meta-analysis Open

S P Leighton, L Nerurkar, R Krishnadas, C Johnman, G J Graham and J Cavanagh

Mol Psychiatry 23: 48-58; advance online publication, November 14, 2017; doi:10.1038/mp.2017.205

The effects of ketamine on dopaminergic function: meta-analysis and review of the implications for neuropsychiatric disorders Open

M Kokkinou, A H Ashok and O D Howes

Mol Psychiatry 23: 59-69; advance online publication, October 3, 2017; doi:10.1038/mp.2017.190

Face and predictive validity of the ClockΔ19 mouse as an animal model for bipolar disorder: a systematic review

M Kristensen, A A Nierenberg and S D Østergaard

Mol Psychiatry 23: 70-80; advance online publication, November 7, 2017; doi:10.1038/mp.2017.192

Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease

S Hunter and C Brayne

Mol Psychiatry 23: 81-93; advance online publication, November 7, 2017; doi:10.1038/mp.2017.218

Purinergic system in psychiatric diseases

A Cheffer, A R G Castillo, J Corrêa-Velloso, M C B Gonçalves, Y Naaldijk, I C Nascimento, G Burnstock and H Ulrich

Mol Psychiatry 23: 94-106; advance online publication, September 26, 2017; doi:10.1038/mp.2017.188

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Original Articles

Dynamic landscape of the local translation at activated synapses Open

T M Khlebodarova, V V Kogai, E A Trifonova and V A Likhoshvai

Mol Psychiatry 23: 107-114; advance online publication, December 5, 2017; doi:10.1038/mp.2017.245

Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay

M R Lee, K B Scheidweiler, X X Diao, F Akhlaghi, A Cummins, M A Huestis, L Leggio and B B Averbeck

Mol Psychiatry 23: 115-122; advance online publication, March 14, 2017; doi:10.1038/mp.2017.27

MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice

A C Mitchell, B Javidfar, V Pothula, D Ibi, E Y Shen, C J Peter, L K Bicks, T Fehr, Y Jiang, K J Brennand, R L Neve, J Gonzalez-Maeso and S Akbarian

Mol Psychiatry 23: 123-132; advance online publication, January 24, 2017; doi:10.1038/mp.2016.254

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

R C Culverhouse, N L Saccone, A C Horton, Y Ma, K J Anstey, T Banaschewski, M Burmeister, S Cohen-Woods, B Etain, H L Fisher, N Goldman, S Guillaume, J Horwood, G Juhasz, K J Lester, L Mandelli, C M Middeldorp, E Olié, S Villafuerte, T M Air, R Araya, L Bowes, R Burns, E M Byrne, C Coffey, W L Coventry, K A B Gawronski, D Glei, A Hatzimanolis, J-J Hottenga, I Jaussent, C Jawahar, C Jennen-Steinmetz, J R Kramer, M Lajnef, K Little, H M zu Schwabedissen, M Nauck, E Nederhof, P Petschner, W J Peyrot, C Schwahn, G Sinnamon, D Stacey, Y Tian, C Toben, S Van der Auwera, N Wainwright, J-C Wang, G Willemsen, I M Anderson, V Arolt, C Åslund, G Bagdy, B T Baune, F Bellivier, D I Boomsma, P Courtet, U Dannlowski, E J C de Geus, J F W Deakin, S Easteal, T Eley, D M Fergusson, A M Goate, X Gonda, H J Grabe, C Holzman, E O Johnson, M Kennedy, M Laucht, N G Martin, M R Munafò, K W Nilsson, A J Oldehinkel, C A Olsson, J Ormel, C Otte, G C Patton, B W J H Penninx, K Ritchie, M Sarchiapone, J M Scheid, A Serretti, J H Smit, N C Stefanis, P G Surtees, H Völzke, M Weinstein, M Whooley, J I Nurnberger Jr, N Breslau and L J Bierut

Mol Psychiatry 23: 133-142; advance online publication, April 4, 2017; doi:10.1038/mp.2017.44

Acute engagement of Gq-mediated signaling in the bed nucleus of the stria terminalis induces anxiety-like behavior

C M Mazzone, D Pati, M Michaelides, J DiBerto, J H Fox, G Tipton, C Anderson, K Duffy, J M McKlveen, J A Hardaway, S T Magness, W A Falls, S E Hammack, Z A McElligott, Y L Hurd and T L Kash

Mol Psychiatry 23: 143-153; advance online publication, December 13, 2016; doi:10.1038/mp.2016.218

A genome-wide gene-by-trauma interaction study of alcohol misuse in two independent cohorts identifies PRKG1 as a risk locus

R Polimanti, J Kaufman, H Zhao, H R Kranzler, R J Ursano, R C Kessler, J Gelernter and M B Stein

Mol Psychiatry 23: 154-160; advance online publication, March 7, 2017; doi:10.1038/mp.2017.24

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Corrigenda

Predicting educational achievement from DNA Open

S Selzam, E Krapohl, S von Stumm, P F O'Reilly, K Rimfeld, Y Kovas, P S Dale, J J Lee and R Plomin

Mol Psychiatry 23: 161; advance online publication, September 26, 2017; doi:10.1038/mp.2017.203

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia Open

S E Legge, M L Hamshere, S Ripke, A F Pardinas, J I Goldstein, E Rees, A L Richards, G Leonenko, L F Jorskog, Clozapine-Induced Agranulocytosis Consortium, K D Chambert, D A Collier, G Genovese, I Giegling, P Holmans, A Jonasdottir, G Kirov, S A McCarroll, J H MacCabe, K Mantripragada, J L Moran, B M Neale, H Stefansson, D Rujescu, M J Daly, P F Sullivan, M J Owen, M C O'Donovan and J T R Walters

Mol Psychiatry 23: 162-163; advance online publication, October 24, 2017; doi:10.1038/mp.2017.214

mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors Open

F Liu, S Laguesse, R Legastelois, N Morisot, S Ben Hamida and D Ron

Mol Psychiatry 23: 164; advance online publication, November 14, 2017; doi:10.1038/mp.2017.252

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Erratum

Toward a conceptual framework for early brain and behavior development in autism Open

J Piven, J T Elison and M J Zylka

Mol Psychiatry 23: 165; advance online publication, October 17, 2017; doi:10.1038/mp.2017.212