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This NIDA news release titled “Endocarditis in patients with cocaine or opioid use disorder markedly increased between 2011 and 2022” highlights the important Molecular Psychiatry publication “Association of COVID-19 with endocarditis in patients with cocaine or opioid use disorders in the US” by Wang L. et al. Click here to learn more.
Behavioural supersensitivity may be a result of increased glutamate sensitivity of D2-MSN and reduced sensitivity to dopamine. We propose that clozapine may address behavioural supersensitivity by modulating glutamate activity which may partially explain its unique effectiveness in the setting of treatment resistant schizophrenia.
We are delighted to present in this collection twelve of Molecular Psychiatry's highest-impact articles from 2022, selected by Editor-in-Chief Julio Licinio.