Volume 15

  • No. 6 June 2022

    The cover image is a scanning electron micrograph of murine small intestine during infection with the helminth parasite,Heligmosomoides polygyrus. False colouring (purple) highlights the worm, in close contact with mucus and intestinal tissue. The image was taken at day 21 of infection in the upper duodenum. Microscopy by Dr Leandro Lemgruber from the Glasgow Imaging Facility, University of Glasgow, UK.

  • No. 5 May 2022

    This cover image shows immunostaining SARS-CoV-2- infected paediatric bronchial epithelial cells. Cross-sections of highly differentiated air-liquid interface cultures were fi xed fi ve days postinfection with SARS-CoV-2 and stained for nucleocapsid protein (magenta), the mucin MUC5AC (yellow) and basal cell marker KRT5 (cyan).

  • No. 4 April 2022

     Maximum projection image obtained using intravital microscopy to visualize the jejunal mucosa of a GFP γδ T cell transgenic mouse (TcrdEGFP). An altered microbiota results in expansion of the γδ IEL compartment. Green, γδ T cells; magenta, lumen; cyan, nuclei.

  • No. 3 May 2022

     This cover image shows the immunostaining of a gastric tissue section after H. pylori infection which is stained for eosinophil-peroxidase in eosinophils (red) and Foxp3 in regulatory T-cells (turquoise), nuclei were counterstained with Hoechst 33342 (blue). The image shows the infi ltration of eosinophils and regulatory T-cells into the H. pylori-infected gastric tissue and the co-localization of the two cell types in the mucosa.

  • No. 2 February 2022

     Adult Heligmosomoides polygyrus isolated from the small intestine of mouse. Photo Ada Lerma Clavero/ Cajsa Classon

  • No. 1 January 2022

    This image shows the immunostaining of whole-mount villi structures from the mouse ileum. Axons were stained with a pan-neuronal marker PGP9.5 (green). Some epithelial cells, presumably enteroendocrine cells, are also stained positive with PGP9.5. Vasculatures for villi were labelled with VEGFR-2 as shown in magenta.