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Original Manuscript |
Resistance to cytarabine and gemcitabine and in vitro selection of transduced cells after retroviral expression of cytidine deaminase in human hematopoietic progenitor cells
- W Bardenheuer
- , K Lehmberg
- , I Rattmann
- , A Brueckner
- , A Schneider
- , U R Sorg
- , S Seeber
- , T Moritz
- & M Flasshove
-
Original Manuscript |
Long-term results in children with AML: NOPHO-AML Study Group – report of three consecutive trials
- S O Lie
- , J Abrahamsson
- , N Clausen
- , E Forestier
- , H Hasle
- , L Hovi
- , G Jonmundsson
- , L Mellander
- , M A Siimes
- , M Yssing
- , B Zeller
- & G Gustafsson
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Original Manuscript |
Successive clinical trials for childhood acute myeloid leukemia at St Jude Children's Research Hospital, from 1980 to 2000
- R C Ribeiro
- , B I Razzouk
- , S Pounds
- , N Hijiya
- , C-H Pui
- & J E Rubnitz
-
Original Manuscript |
Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia
- D H Christiansen
- , M K Andersen
- , F Desta
- & J Pedersen-Bjergaard
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Original Manuscript |
Differential expression of NF-κB pathway genes among peripheral T-cell lymphomas
- B Martínez-Delgado
- , M Cuadros
- , E Honrado
- , A Ruiz de la Parte
- , G Roncador
- , J Alves
- , J M Castrillo
- , C Rivas
- & J Benítez
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Original Manuscript |
Aberrant promoter methylation of the retinoic acid receptor alpha gene in acute promyelocytic leukemia
- C-S Chim
- , S-Y Wong
- , A Pang
- , P Chu
- , J S Lau
- , K-F Wong
- & Y-L Kwong
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Original Manuscript |
TNFα stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells
- F Guilloton
- , A de Thonel
- , C Jean
- , C Demur
- , V Mansat-De Mas
- , G Laurent
- & A Quillet-Mary
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Original Manuscript |
Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice
- U Siegler
- , C P Kalberer
- , P Nowbakht
- , S Sendelov
- , S Meyer-Monard
- & A Wodnar-Filipowicz
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Original Manuscript |
Sensitivity of human multiple myelomas and myeloid leukemias to the proteasome inhibitor I
- F Servida
- , D Soligo
- , D Delia
- , C Henderson
- , C Brancolini
- , L Lombardi
- & G Lambertenghi Deliliers
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Original Manuscript |
Evidence for involvement of clonally expanded CD8+ T cells in anticancer immune responses in CLL patients following nonmyeloablative conditioning and hematopoietic cell transplantation
- T Kollgaard
- , S L Petersen
- , S Reker Hadrup
- , T N Masmas
- , T Seremet
- , M H Andersen
- , H O Madsen
- , L Vindeløv
- & P thor Straten
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Original Manuscript |
CD44 ligation induces apoptosis via caspase- and serine protease-dependent pathways in acute promyelocytic leukemia cells
- E Maquarre
- , C Artus
- , Z Gadhoum
- , C Jasmin
- , F Smadja-Joffe
- & J Robert-Lézénès
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Original Manuscript |
CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation
- B T Pittner
- , T D Shanafelt
- , N E Kay
- & D F Jelinek
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Original Manuscript |
Twenty years of Polish experience with three consecutive protocols for treatment of childhood acute myelogenous leukemia
- A Dluzniewska
- , W Balwierz
- , J Armata
- , A Balcerska
- , A Chybicka
- , J Kowalczyk
- , M Matysiak
- , M Ochocka
- , U Radwanska
- , R Rokicka-Milewska
- , D Sonta-Jakimczyk
- , J Wachowiak
- & M Wysocki
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Original Manuscript |
FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma
- G Roncador
- , J F Garcia
- , J F Garcia
- , L Maestre
- , E Lucas
- , J Menarguez
- , K Ohshima
- , S Nakamura
- , A H Banham
- & M A Piris
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Original Manuscript |
Cleavage of the MLL gene by activators of apoptosis is independent of topoisomerase II activity
- C J Betti
- , M J Villalobos
- , Q Jiang
- , E Cline
- , M O Diaz
- , G Loredo
- & A T M Vaughan
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Original Manuscript |
Refinement of the international prognostic scoring system (IPSS) by including LDH as an additional prognostic variable to improve risk assessment in patients with primary myelodysplastic syndromes (MDS)
- U Germing
- , B Hildebrandt
- , M Pfeilstöcker
- , T Nösslinger
- , P Valent
- , C Fonatsch
- , M Lübbert
- , D Haase
- , C Steidl
- , O Krieger
- , R Stauder
- , A A N Giagounidis
- , C Strupp
- , A Kündgen
- , T Mueller
- , R Haas
- , N Gattermann
- & C Aul
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Original Manuscript |
Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT)
- M Aoudjhane
- , M Labopin
- , N C Gorin
- , A Shimoni
- , T Ruutu
- , H-J Kolb
- , F Frassoni
- , J M Boiron
- , J L Yin
- , J Finke
- , H Shouten
- , D Blaise
- , M Falda
- , A A Fauser
- , J Esteve
- , E Polge
- , S Slavin
- , D Niederwieser
- , A Nagler
- & V Rocha
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Original Manuscript |
Cyclophosphamide followed by fludarabine for untreated chronic lymphocytic leukemia: a phase II SWOG TRIAL 9706
- M A Hussein
- , H Gundacker
- , D R Head
- , L Elias
- , K A Foon
- , D H Boldt
- , S M Dobin
- , S R Dakhil
- , G T Budd
- & F R Appelbaum
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Original Manuscript |
Translocation t(14;18) and gain of chromosome 18/BCL2: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas
- E Galteland
- , E A Sivertsen
- , D H Svendsrud
- , L Smedshammer
- , S H Kresse
- , L A Meza-Zepeda
- , O Myklebost
- , Z Suo
- , D Mu
- , P M DeAngelis
- & T Stokke
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Original Manuscript |
Transfection of antisense core 2 β1,6-N-acetylglucosaminyltransferase-1 cDNA suppresses selectin ligand expression and tissue infiltration of B-cell precursor leukemia cells
- J Kikuchi
- , H Ozaki
- , C Nonomura
- , H Shinohara
- , S Iguchi
- , H Nojiri
- , H Hamada
- , A Kiuchi
- & M Nakamura
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Original Manuscript |
Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells
- C J Yao
- , K Works
- , P A Romagnoli
- & G E Austin
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Original Manuscript |
Relation between genetic variants of the ataxia telangiectasia-mutated (ATM) gene, drug resistance, clinical outcome and predisposition to childhood T-lineage acute lymphoblastic leukaemia
- M Meier
- , M L den Boer
- , A G Hall
- , J A E Irving
- , M Passier
- , L Minto
- , E R van Wering
- , G E Janka-Schaub
- & R Pieters
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Original Manuscript |
Risk factors of myelodysplastic syndromes: a case–control study
- S S Strom
- , Y Gu
- , S K Gruschkus
- , S A Pierce
- & E H Estey
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Original Manuscript |
Therapy-related leukemia: clinical characteristics and analysis of new molecular risk factors in 96 adult patients
- D Rund
- , S Krichevsky
- , S Bar-Cohen
- , N Goldschmidt
- , M Kedmi
- , E Malik
- , A Gural
- , S Shafran-Tikva
- , S Ben-Neriah
- & D Ben-Yehuda
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Original Manuscript |
Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells
- C Chuah
- , D J Barnes
- , M Kwok
- , A Corbin
- , M W N Deininger
- , B J Druker
- & J V Melo
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Original Manuscript |
Treatment strategies and long-term results in paediatric patients treated in four consecutive AML-BFM trials
- U Creutzig
- , M Zimmermann
- , J Ritter
- , D Reinhardt
- , J Hermann
- , G Henze
- , H Jürgens
- , H Kabisch
- , A Reiter
- , H Riehm
- , H Gadner
- & G Schellong
-
Original Manuscript |
Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation
- W Zhang
- , T McQueen
- , W Schober
- , G Rassidakis
- , M Andreeff
- & M Konopleva
-
Original Manuscript |
Imatinib mesylate suppresses cytokine synthesis by activated CD4 T cells of patients with chronic myelogenous leukemia
- H Gao
- , B-N Lee
- , M Talpaz
- , N J Donato
- , J E Cortes
- , H M Kantarjian
- & J M Reuben
-
Original Manuscript |
Low-dose cytosine arabinoside (LD-AraC) vs LD-AraC plus granulocyte/macrophage colony stimulating factor vs LD-AraC plus Interleukin-3 for myelodysplastic syndrome patients with a high risk of developing acute leukemia: final results of a randomized phase III study (06903) of the EORTC Leukemia Cooperative Group
- H Zwierzina
- , S Suciu
- , J Loeffler-Ragg
- , R Neuwirtova
- , P Fenaux
- , M Beksac
- , J Harousseau
- , V Nuessler
- , J Cermak
- , G Solbu
- , R Willemze
- , T de Witte
- & S Amadori
-
Original Manuscript |
Long-term results of children with acute myeloid leukemia: a report of three consecutive Phase III trials by the Children's Cancer Group: CCG 251, CCG 213 and CCG 2891
- F O Smith
- , T A Alonzo
- , R B Gerbing
- , W G Woods
- & R J Arceci
-
Original Manuscript |
Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): a review of four consecutive childhood AML trials conducted between 1981 and 2000
- Y Ravindranath
- , M Chang
- , C P Steuber
- , D Becton
- , G Dahl
- , C Civin
- , B Camitta
- , A Carroll
- , S C Raimondi
- & H J Weinstein
-
Original Manuscript |
Results of 58872 and 58921 trials in acute myeloblastic leukemia and relative value of chemotherapy vs allogeneic bone marrow transplantation in first complete remission: the EORTC Children Leukemia Group report
- N Entz-Werle
- , S Suciu
- , J van der Werff ten Bosch
- , E Vilmer
- , Y Bertrand
- , Y Benoit
- , G Margueritte
- , E Plouvier
- , P Boutard
- , E Vandecruys
- , A Ferster
- , P Lutz
- , A Uyttebroeck
- , C Hoyoux
- , A Thyss
- , X Rialland
- , L Norton
- , M-P Pages
- , N Philippe
- , J Otten
- & C Behar
-
Original Manuscript |
Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development
- A Burchert
- , Y Wang
- , D Cai
- , N von Bubnoff
- , P Paschka
- , S Müller-Brüsselbach
- , O G Ottmann
- , J Duyster
- , A Hochhaus
- & A Neubauer
-
Original Manuscript |
Fludarabine plus cyclophosphamide in Waldenström's macroglobulinemia: results in 49 patients
- J Tamburini
- , V Lévy
- , C Chaleteix
- , J P Fermand
- , A Delmer
- , L Stalniewicz
- , P Morel
- , F Dreyfus
- , M J Grange
- , B Christian
- , S Choquet
- & V Leblond
-
Original Manuscript |
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
- C A Bradbury
- , F L Khanim
- , R Hayden
- , C M Bunce
- , D A White
- , M T Drayson
- , C Craddock
- & B M Turner
-
Original Manuscript |
Treatment of childhood acute myeloblastic leukemia: dose intensification improves outcome and maintenance therapy is of no benefit – multicenter studies of the French LAME (Leucémie Aiguë Myéloblastique Enfant) Cooperative Group
- Y Perel
- , A Auvrignon
- , T Leblanc
- , G Michel
- , Y Reguerre
- , J-P Vannier
- , J-H Dalle
- , V Gandemer
- , C Schmitt
- , F Méchinaud
- , O Lejars
- , C Piguet
- , G Couillaud
- , B Pautard
- , J Landman-Parker
- , I Thuret
- , N Aladjidi
- , A Baruchel
- & G Leverger
-
Original Manuscript |
CDK2 catalytic activity and loss of nuclear tethering of retinoblastoma protein in childhood acute lymphoblastic leukemia
- N M R Schmitz
- , K Leibundgut
- & A Hirt
-
Original Manuscript |
Translational study of vitamin D differentiation therapy of myeloid leukemia: effects of the combination with a p38 MAPK inhibitor and an antioxidant
- Q Wang
- , J S Harrison
- , M Uskokovic
- , A Kutner
- & G P Studzinski
-
Original Manuscript |
Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia
- T Lehrnbecher
- , T Bernig
- , M Hanisch
- , U Koehl
- , M Behl
- , D Reinhardt
- , U Creutzig
- , T Klingebiel
- , S J Chanock
- & D Schwabe
-
Original Manuscript |
Retinoid/arsenic combination therapy of promyelocytic leukemia: induction of telomerase-dependent cell death
- I Tarkanyi
- , C Dudognon
- , J Hillion
- , F Pendino
- , M Lanotte
- , J Aradi
- & E Ségal-Bendirdjian
-
Original Manuscript |
Treatment and long-term results in children with acute myeloid leukaemia treated according to the AIEOP AML protocols
- A Pession
- , R Rondelli
- , G Basso
- , C Rizzari
- , A M Testi
- , F Fagioli
- , P De Stefano
- & F Locatelli
-
Original Manuscript |
Treatment strategy and results in children treated on three Dutch Childhood Oncology Group acute myeloid leukemia trials
- G Kardos
- , C M Zwaan
- , G J L Kaspers
- , S S N de-Graaf
- , E S J M de Bont
- , A Postma
- , J P M Bökkerink
- , R S Weening
- , A van der Does-van den Berg
- , E R van Wering
- , C Korbijn
- & K Hählen
-
Original Manuscript |
CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes
- W A Dik
- , W Brahim
- , C Braun
- , V Asnafi
- , N Dastugue
- , O A Bernard
- , J J M van Dongen
- , A W Langerak
- , E A Macintyre
- & E Delabesse
-
Original Manuscript |
Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia
- Y-S Meng
- , H Khoury
- , J E Dick
- & M D Minden
-
Original Manuscript |
Increased expression of CD152 (CTLA-4) by normal T lymphocytes in untreated patients with B-cell chronic lymphocytic leukemia
- M Motta
- , L Rassenti
- , B J Shelvin
- , S Lerner
- , T J Kipps
- , M J Keating
- & W G Wierda
-
Original Manuscript |
Cytogenetic analysis delineates a spectrum of chromosomal changes that can distinguish non-MALT marginal zone B-cell lymphomas among mature B-cell entities: a description of 103 cases
- E Callet-Bauchu
- , L Baseggio
- , P Felman
- , A Traverse-Glehen
- , F Berger
- , D Morel
- , S Gazzo
- , C Poncet
- , C Thieblemont
- , B Coiffier
- , J P Magaud
- & G Salles
-
Original Manuscript |
Clinical and biological relevance of single-nucleotide polymorphisms and acquired somatic mutations of the BCL6 first intron in follicular lymphoma
- F Jardin
- , P Ruminy
- , F Parmentier
- , J M Picquenot
- , M N Courel
- , P Bertrand
- , G Buchonnet
- , H Tilly
- & C Bastard
-
Original Manuscript |
Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells
- J K Warner
- , J C Y Wang
- , K Takenaka
- , S Doulatov
- , J L McKenzie
- , L Harrington
- & J E Dick
-
Original Manuscript |
Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin
- H Quentmeier
- , M P Martelli
- , W G Dirks
- , N Bolli
- , A Liso
- , R A F MacLeod
- , I Nicoletti
- , R Mannucci
- , A Pucciarini
- , B Bigerna
- , M F Martelli
- , C Mecucci
- , H G Drexler
- & B Falini
