Journal Information

On this page: Aims and scope of journal | Our publishing models | Impact Factor | Abstracted/indexed in | ISSN and eISSN | Newsfeeds

Aims and scope of journal

Laboratory Investigation is an international journal owned by the United States and Canadian Academy of Pathology. Laboratory Investigation offers prompt publication of high-quality original research in all biomedical disciplines relating to the understanding of human disease and the application of new methods to the diagnosis of disease. Both human and experimental studies are welcome.


  • Original Articles: Original research exploring mechanisms of disease pathogenesis. This includes structural and molecular pathogenesis of disease; mechanisms underlying the morphologic manifestations of disease; or translation of basic research findings into advances in assessment of human disease by laboratory diagnostic methodologies.
  • Technical Reports: Novel technical advances in the diagnosis of human disease or in the investigation of human or experimental disease. Advances must be substantive and of general interest. These are not short reports nor lesser papers than Original Articles.
  • Mini-Reviews and Review Articles
  • Pathobiology in Focus (by invitation only): Succinct critical reviews, commentaries, or controversies in mechanisms of human disease, as well as updates on seminal technological breakthroughs. The intent of this series is to facilitate understanding and discussion on burgeoning issues in science with an emphasis on disease mechanisms.

Submit your next manuscript to Laboratory Investigation and benefit from:

  • International and highly respected editorial team
  • Rapid decision and publication times
  • Wide exposure and article visibility via
  • Owned by the United States and Canadian Academy of Pathology, the global leader in pathology education
  • Articles promoted via Twitter and online topical Collections
  • Free advice from Springer Nature’s Research Data Services
  • Share your article through SharedIt - Springer Nature’s content-sharing initiative allowing authors and subscribers to share links to view-only, full-text articles from this journal

Our publishing models   

Laboratory Investigation is a Transformative Journal (TJ). When research is accepted for publication, authors can choose to publish using either the traditional publishing route OR via immediate gold Open Access. 

Laboratory Investigation is actively committed to becoming a fully Open Access journal. We will increase the number of articles we publish OA, with the eventual goal of becoming a fully Open Access journal. A journal that commits to this process is known as a Transformative Journal. 

Find out more about Transformative Journals

Authors may need to take specific actions to achieve compliance with funder and institutional open access mandates. If your research is supported by a funder that requires immediate open access (e.g. according to Plan S principles) then you should select the gold OA route, and we will direct you to the compliant route where possible. For authors selecting the subscription publication route our standard licensing terms will need to be accepted including our self-archiving policies. Those standard licensing terms will supersede any other terms that the author or any third party may assert apply to any version of the manuscript.

Journal Metrics

Article metrics such as number of downloads, citations and online attention are available from each article page, and provide an overview of the attention received by a paper.

The 2020 peer review performance metrics for Laboratory Investigation are shown below:

Average time to decision without external review - 3 days
Average time to decision following external review - 35 days
Article page views - 543,463

The 2020 journal metrics* for Laboratory Investigation are as follows:

2-year Impact Factor*: 5.662
5-year Impact Factor*: 5.391
Immediacy index*: 1.653
Eigenfactor® score*: 0.00824
Article influence score*: 1.253
JCR Rank*: PATHOLOGY 11/77
Journal Citation Score*: 1.6

SNIP: 1.216
SJR: 1.542

*2020 Journal Citation Reports® Science Edition (Clarivate Analytics, 2020)

Abstracted/indexed in

Index Medicus
Current Contents (Life Sciences, Science Citation Index, Research Alert, ISI/BioMed)
Excerpta Medica
Biosciences Information Service
Reference Update/Research Information Services


The international standard serial number (ISSN) for Laboratory Investigation is 0023-6837 and the electronic international standard serial number (eISSN) is 1530-0307.


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