Welcome to Laboratory Investigation

Advancing the understanding of human and experimental disease

Announcements

  • Visualization of segmented steatosis droplets

    Biology has evolved greatly in the past decade as high-throughput technologies were developed and applied to various biological disciplines. These technologies have generated an unprecedented amount and new types of biological data and how to make sense of “big data” is an emerging technological and conceptual challenge.

  • Immunofluorescent staining of human melanocytic specimens

    This Collection highlights the newest top-viewed content from Laboratory Investigation. Updated each month, we hope you enjoy reading this selection of articles. Laboratory Investigation aims to publish high-quality original research in all biomedical disciplines relating to the understanding of human disease and the application of new methods to the diagnosis of disease.

  • Pseudo-color rendering of fluorescence-like representations of non-small cell lung cancer

    Brightfield microscopy is the preferred method of pathologists for diagnosing solid tumors, utilizing common staining techniques such as hematoxylin and eosin staining and immunohistochemistry. This collection of articles describe new ways to process samples and interpret data generated by histopathology and immunohistochemistry, as well as new technologies that complement these methods.

  • Immunofluorescent staining of a mouse cardiac section with lectins

    The editors of Laboratory Investigation present a collection of recent papers that explore the relationships between changes in the mammalian glycome and pathobiology. These studies describe new roles for glycans in heart disease, neurodegenerative diseases, genetic disorders, and several types of cancer.

Laboratory Investigation is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.

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