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Efficient tools for monitoring fibrosis-related changes in neovascular age-related macular degeneration are lacking. Linder et al. describe the first use of fluorescently labeled collagen hybridizing peptides to directly image collagen remodeling and monitor fibrosis in two mouse models of ocular neovascularization.
This study reports the use of fluorescently labeled collagen hybridizing peptides to directly image collagen remodeling and monitor fibrosis in two mouse models of ocular neovascularization.
Pairing palatable formulations with micropipette dosing for administration of water-insoluble drugs such as tamoxifen in mice promotes voluntary consumption without loss of efficacy compared to more invasive administration methods.