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In this Review, the authors identify and compare available pig models in pain research. They also describe the different pain assessment methods used in pigs and compare them with the pain assessment methods used in humans to identify overlaps and possible improvements.
Rodent grooming is an important behaviour that is commonly used to characterize preclinical models of human brain disorders. A new paper has leveraged deep learning to develop a precise, high throughput and automated grooming classifier to facilitate mechanistic neuroscience research on grooming.
In this review, the authors compare 28 freely available animal-tracking software applications, highlighting the strengths and weaknesses of the applications in the tracking pipeline, from video acquisition to trajectory generation and data analysis.
In this review, the authors describe how the use of touchscreen-equipped apparatus in behavioral sciences can facilitate the implementation of the 3Rs principles in this discipline and offer a new platform to monitor laboratory animal welfare.
Social isolation can lead to poor mental and physical health. A new study determines that social isolation increases food and nicotine-seeking during abstinence, but that social housing can reverse these effects.
A new CRISPR/Cas9 method that can generate F0 mutant zebrafish has the potential to cut costs, spare time, and reduce animal use for researchers interested in screening loss-of-function alleles in vivo.
In this perspective, the authors discuss the use of Caenorhabditis elegans as a model system to study host–microbe interactions, highlighting innovative methodologies and key findings from recent studies.