Severe bleeding after childbirth – postpartum haemorrhage (PPH) – is a leading cause of maternal mortality worldwide. Several animal models have been developed for testing novel therapeutic materials; however, these animals differ considerably from the anatomy and physiology of a postpartum woman. In a new Review, Hargett, Leslie et al. critically evaluate available animal models of PPH and propose additional methods for modeling PPH in vivo.

See Gaharwar et al.

Data sharing allows data to be reused in other analyses, avoiding resources (and animals) being wasted in unnecessary replication studies. A new Perspective proposes a minimal metadata set to enable data sharing and repurposing in animal research, contributing to the principle of reduction.

See Moresis et al.

Positioning and maintaining small animals for imaging over time requires a means to secure the head, maintain the animal's body temperature and facilitate delivery of anesthesia if needed. A new Article describes an open-source, customizable 3D printable cradle design that can be used for brain imaging in awake mice and anesthetized mice and rats.

See Yaghmazadeh et al.

Nonhuman primate neuroimaging is a rapidly growing and extremely promising area of neuroscience research that suffers from a lack of data. Neuroimaging database sharing can accelerate research in this field, while limiting the number of animals used. A new Article presents The PREMISE database, a PET/MR dataset of Macaca Fascicularis brain images structured according to BIDS standards and available for researchers.

See Becker et al.