In this Perspective, the authors summarize the current knowledge on the post-COVID-19 condition, focusing on the neurological manifestations, and discuss the applicability of existing animal models to recapitulate human condition.

Two Cre-dependent reporter mice, oFluc and Akaluc, were created and tested for bioluminescence in neural tissues and organs. Both strains were brighter than the classical luciferase Luc2, potentially facilitating in vivo bioluminescence imaging of various tissues.

Sharing research tools and data with other scientists brings many benefits, such as using fewer animals, improving reproducibility and increasing study sample size, but the practice still needs to be more widely adopted.

Unpredictable chronic stress (UCS) increases anxiety/fear-related behavior and cortisol levels while decreasing locomotor performance, according to a systematic analysis of 38 studies on UCS in zebrafish. To further assess the effects of UCS on zebrafish behavior, future well-designed trials are required.

Two Cre-dependent reporter mice, oFluc and Akaluc, were created and tested for bioluminescence in neural tissues and organs. Both strains were brighter than the classical luciferase Luc2, potentially facilitating in vivo bioluminescence imaging of various tissues.

The authors developed an R package that enables the estimation of group size required for mouse breeding, taking into account Mendelian genetics, fertility and litter size.

This protocol describes a humanized mouse model created using neonatal thymus and umbilical cord blood hematopoietic stem cells as nonfetal human tissue sources.

The authors investigated the influence of housing density and bedding volume on ammonia build-up in two individually ventilated mouse cages models. While the amount of bedding had no influence on ammonia levels, smaller Type II individually ventilated cages accumulated higher ammonia levels than larger Type III individually ventilated cages, even at similar housing densities.

A mouse model to study norovirus pathogenesis is described. The murine norovirus strain WU23, originally isolated from an intestinal site, induces severe but self-resolving diarrhea in neonates, reflecting the pathology observed during human norovirus infection.