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LabAnimal is a Nature Research journal covering in vivo science & technology using model organisms of human health and disease. 

Latest Research

  • Article |

    Poon, Y-Y et al. re-visit the effects of isoflurane on cardiovascular functions by measuring temporal changes in blood pressure, heart rate, cardiac performance, baroreflex-mediated sympathetic vasomotor tone, cardiac vagal baroreflex, functional connectivity within baroreflex neural circuits, carotid or cerebral blood flow, respiratory rate and blood gas in mice exposed to 1.5% (vol/vol) isoflurane.

    • Yan-Yuen Poon
    • , Ching-Yi Tsai
    • , Ya‐Hui Huang
    • , Jacqueline C. C. Wu
    • , Samuel H. H. Chan
    •  & Julie Y. H. Chan
  • Protocol |

    This protocol describes the different steps to establish a murine model of restenosis after angioplasty of a stenotic arteriovenous fistula (AVF), including a detailed description of the partial nephrectomy procedure to induce chronic kidney disease, the AVF procedure for development of de novo stenosis and the angioplasty treatment associated with progression of restenosis.

    • Chuanqi Cai
    • , Chenglei Zhao
    • , Sreenivasulu Kilari
    • , Amit Sharma
    • , Avishek K. Singh
    • , Michael L. Simeon
    • , Avanish Misra
    • , Yiqing Li
    •  & Sanjay Misra
  • Article |

    Continuous motion monitoring sensitively predicts terminal endpoint in a mouse model of ovarian cancer; the use of motion metrics could reduce animal suffering and be valuable for drug efficacy testing.

    • Chibueze D. Nwagwu
    • , Erwin Defensor
    • , Michael Y. Jiang
    • , Danelle A. Rolle-McFarland
    • , Anne-Marie E. Carbonell
    •  & W. Shawn Carbonell
  • Review Article |

    This Review discusses the strengths of the zebrafish model for microbiome research, and highlights important insights gleaned from observational and manipulative microbiome studies in zebrafish.

    • Keaton Stagaman
    • , Thomas J. Sharpton
    •  & Karen Guillemin

News & Comment

About the Journal

  • LabAnimal’s focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.

  • LabAnimal publishes a range of content types including reviews and perspectives, research articles, methods-based columns, as well as news and technology features.

  • All editorial decisions at LabAnimal are made by a dedicated team of full-time professional editors. In addition, LabAnimal has an Editorial Advisory Panel in all areas of in vivo science, technology and policy.

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For Authors & Referees

  • Please read this section before submitting anything to LabAnimal. This section explains our editorial criteria, and how manuscripts are handled by our editors between submission and acceptance for publication.

  • Explanation of the submission, peer-review, decision and revision processes.

  • This section contains guidelines for refereeing for LabAnimal.


Lab Animal Microbiome Collection

A collection of Microbiome-related research, reviews, and news published in Lab Animal