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LabAnimal is a Nature Research journal covering in vivo science & technology using model organisms of human health and disease. 

Latest Research

  • Protocol |

    This protocol describes the different steps to establish a murine model of restenosis after angioplasty of a stenotic arteriovenous fistula (AVF), including a detailed description of the partial nephrectomy procedure to induce chronic kidney disease, the AVF procedure for development of de novo stenosis and the angioplasty treatment associated with progression of restenosis.

    • Chuanqi Cai
    • , Chenglei Zhao
    • , Sreenivasulu Kilari
    • , Amit Sharma
    • , Avishek K. Singh
    • , Michael L. Simeon
    • , Avanish Misra
    • , Yiqing Li
    •  & Sanjay Misra
  • Article |

    Continuous motion monitoring sensitively predicts terminal endpoint in a mouse model of ovarian cancer; the use of motion metrics could reduce animal suffering and be valuable for drug efficacy testing.

    • Chibueze D. Nwagwu
    • , Erwin Defensor
    • , Michael Y. Jiang
    • , Danelle A. Rolle-McFarland
    • , Anne-Marie E. Carbonell
    •  & W. Shawn Carbonell
  • Review Article |

    This Review discusses the strengths of the zebrafish model for microbiome research, and highlights important insights gleaned from observational and manipulative microbiome studies in zebrafish.

    • Keaton Stagaman
    • , Thomas J. Sharpton
    •  & Karen Guillemin
  • Protocol |

    Goblet cell–associated antigen passages can deliver luminal substances to antigen-presenting cells to induce antigen-specific T cell responses. This protocol describes how to identify and quantify intestinal epithelial cells that have the capacity to take up luminal substances, by intraluminal injection of fluorescent dextran, tissue sectioning for slide preparation and imaging with fluorescence microscopy.

    • Kathryn A. Knoop
    • , Devesha H. Kulkarni
    • , Keely G. McDonald
    • , Jenny K. Gustafsson
    • , Jazmyne E. Davis
    • , Alexandria N. Floyd
    •  & Rodney D. Newberry

News & Comment

About the Journal

  • LabAnimal’s focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.

  • LabAnimal publishes a range of content types including reviews and perspectives, research articles, methods-based columns, as well as news and technology features.

  • All editorial decisions at LabAnimal are made by a dedicated team of full-time professional editors. In addition, LabAnimal has an Editorial Advisory Panel in all areas of in vivo science, technology and policy.

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  • Please read this section before submitting anything to LabAnimal. This section explains our editorial criteria, and how manuscripts are handled by our editors between submission and acceptance for publication.

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Lab Animal Microbiome Collection

A collection of Microbiome-related research, reviews, and news published in Lab Animal