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LabAnimal is a Nature Research journal covering in vivo science & technology using model organisms of human health and disease. 

  • Sina M. Schalbetter
  • Flavia S. Mueller
  • Tina Notter
Article

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  • In this perspective, the authors discuss the use of Caenorhabditis elegans as a model system to study host–microbe interactions, highlighting innovative methodologies and key findings from recent studies.

    • Cassandra Backes
    • Daniel Martinez-Martinez
    • Filipe Cabreiro
    Perspective
  • A new rat model of brainstem ischemia is described. Selective ligation of four points of the lower basilar artery causes a localized brainstem ischemic lesion in adult rats, resulting in hemiparesis, as well as abnormal posture, body balance and locomotion.

    • Ai Namioka
    • Takahiro Namioka
    • Osamu Honmou
    Protocol
  • Preece, Alghadban et al. explore the use of naturally sterile hybrids as an alternative to vasectomized males for the production of pseudopregnant female mice for embryo transfer. Sterile hybrids can contribute to the refinement of the procedure by avoiding a surgical intervention associated with pain and discomfort.

    • Chris Preece
    • Samy Alghadban
    • Benjamin Davies
    Article
  • Poon, Y-Y et al. re-visit the effects of isoflurane on cardiovascular functions by measuring temporal changes in blood pressure, heart rate, cardiac performance, baroreflex-mediated sympathetic vasomotor tone, cardiac vagal baroreflex, functional connectivity within baroreflex neural circuits, carotid or cerebral blood flow, respiratory rate and blood gas in mice exposed to 1.5% (vol/vol) isoflurane.

    • Yan-Yuen Poon
    • Ching-Yi Tsai
    • Julie Y. H. Chan
    Article
  • Aims & Scope

    LabAnimal’s focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.

  • Content Types

    LabAnimal publishes a range of content types including reviews and perspectives, research articles, methods-based columns, as well as news and technology features.

  • About the Editors

    All editorial decisions at LabAnimal are made by a dedicated team of full-time professional editors. In addition, LabAnimal has an Editorial Advisory Panel in all areas of in vivo science, technology and policy.

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  • Guide to Authors

    Please read this section before submitting anything to LabAnimal. This section explains our editorial criteria, and how manuscripts are handled by our editors between submission and acceptance for publication.

  • Editorial Process

    Explanation of the submission, peer-review, decision and revision processes.

  • For Referees

    This section contains guidelines for refereeing for LabAnimal.