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In the past decade, global climate change has come to the forefront of the political and social agenda owing to the growing realization that the Earth's resources are being used in an unsustainable fashion. To highlight the central role of microbial processes in sustainable development, Nature Reviews MicrobiologyandThe ISME Journalpresent a specially commissioned set of articles that highlight the importance of microorganisms in climatic processes and research the generation of new energy sources.