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Long-term variability of systolic blood pressure indicated by root mean square error is significantly associated with a higher risk of type 2 diabetes mellitus in middle-aged Japanese.
The hypertensive cut-off in HBP by HBPM was determined in Japanese pregnant women. (A) Optimizing the polynomial of systolic HBP that induces the hypertensive boundary value by HBPM. By the polynomial equation of mean +3 SD, systolic HBP at 35 weeks gestation equal to non-pregnant was 135 mmHg, the current reference value for non-pregnant hypertension of HBPM. Polynomial of mean +3 SD was considered optimal. (B) Optimization of polynomial of diastolic HBP that induces the hypertensive boundary value by HBPM. By polynomial of mean +2SD, diastolic HBP at 38 weeks gestation equal to non-pregnant was 85 mmHg, the current standard for non-pregnant hypertension by HBPM. Thus, polynomial of mean +2 SD was considered optimal.
The permanent inhabitants exposure to the hypoxia environment long-termly, it may impose negative impact on hypertension. There were 32 studies (86,487 participants) were included for this study review and analyses. We found a curvilinear association between altitude and prevalence of hypertension with peak about 3300 m.
Regarding Japanese primary aldosteronism, the low, intermediate, and high renin change groups (classified based on the response of renin to mineralocorticoid antagonist treatment) had CVD incidence of 2.1%, 0.5%, and 3.7%, respectively, during the 5-year study period.
27 million Japanese are hypertensive disease and 89.6% of them are treated with any anti-hypertensive medications. This is the first study utilizing the National Database of Health Insurance Claims and Specific Health Checkups to determine the number and age-adjusted prevalence of hypertensive patients and treated hypertensive patients in Japan.