Gene Therapy

Cell-Based Therapy

Enhancement of antitumor immunity against B16 melanoma tumor using genetically modified dendritic cells to produce cytokines

Y Akiyama
M Watanabe
K Yamaguchi
Cell-Based Therapy02 Jan 2001
Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells

K S Denis-Mize
M Dupuis
G Ott
Cell-Based Therapy02 Jan 2001
Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I

N Giannoukakis
Z Mi
P Robbins
Cell-Based Therapy04 Dec 2000
Expression of B7.1 (CD80) in a renal cell carcinoma line allows expansion of tumor-associated cytotoxic T lymphocytes in the presence of an alloresponse

DJ Schendel
B Frankenberger
T Blankenstein
Cell-Based Therapy04 Dec 2000
Retroviral vector design studies toward hematopoietic stem cell gene therapy for mucopolysaccharidosis type I

D Pan
E Aronovich
C B Whitley
Cell-Based Therapy06 Nov 2000
The high proliferative potential-quiescent (HPP-Q) cell assay allows an optimized evaluation of gene transfer efficiency into primitive hematopoietic stem/progenitor cells

K Ducos
A Hatzfeld
J Hatzfeld
Cell-Based Therapy25 Oct 2000
Dendritic cells infected with recombinant fowlpox virus vectors are potent and long-acting stimulators of transgene-specific class I restricted T lymphocyte activity

M Brown
Y Zhang
S N Stacey
Cell-Based Therapy02 Oct 2000
Transfected human dendritic cells to induce antitumor immunity

A Rughetti
M Biffoni
M Nuti
Cell-Based Therapy20 Sept 2000
Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR

R A Willemsen
M E M Weijtens
R L H Bolhuis
Cell-Based Therapy21 Aug 2000
Feasibility of CTLA4Ig gene delivery and expression in vivo using retrovirally transduced myeloid dendritic cells that induce alloantigen-specific T cell anergy in vitro

T Takayama
AE Morelli
AW Thomson
Cell-Based Therapy25 Jul 2000
T cell activation by recombinant FcεRI γ-chain immune receptors: an extracellular spacer domain impairs antigen-dependent T cell activation but not antigen recognition

A Hombach
C Heuser
H Abken
Cell-Based Therapy14 Jun 2000
Tumor cells expressing membrane-bound form of IL-4 induce antitumor immunity

Y S Kim
C H Sonn
A L M Bothwell
Cell-Based Therapy25 May 2000
Efficiency of transgenic T cell generation from gene-marked cultured human CD34⁺ cord blood cells is determined by their maturity and the cytokines present in the culture medium

B Verhasselt
E Naessens
J Plum
Cell-Based Therapy25 May 2000
Induction of potent antitumor response by vaccination with tumor lysate-pulsed macrophages engineered to secrete macrophage colony-stimulating factor and interferon-γ

H Lei
D W Ju
X Cao
Cell-Based Therapy03 May 2000
Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zeta

A Annenkov
Y Chernajovsky
Cell-Based Therapy03 May 2000
Efficacy of cancer gene therapy in aging: adenocarcinoma cells engineered to release IL-2 are rejected but do not induce tumor specific immune memory in old mice

M Provinciali
K Argentati
A Tibaldi
Cell-Based Therapy12 Apr 2000
Long-term phenotypic correction of rodent hemiparkinsonism by gene therapy using genetically modified myoblasts

L Cao
Y-C Zhao
Z-C Zheng
Cell-Based Therapy24 Feb 2000
Efficient transduction of mature CD83⁺ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity

H Jonuleit
T Tüting
A H Enk
Cell-Based Therapy17 Feb 2000
The macrophage – a novel system to deliver gene therapy to pathological hypoxia

L Griffiths
K Binley
S Naylor
Cell-Based Therapy17 Feb 2000
Activation of lymphocytes by anti-CD3 single-chain antibody dimers expressed on the plasma membrane of tumor cells

K-W Liao
Y-C Lo
S R Roffler
Cell-Based Therapy17 Feb 2000

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