Table 1 - Correlation of various parameters of esophageal motility disorders: major symptom, clinical syndrome, esophageal motility findings, esophageal bolus transport, pathophysiology or the anatomic site of major involvement

Symptoms	Clinical disorders	Manometric diagnosis	Esophageal transit	Pathophysiology	Anatomic location
DES, diffuse esophageal spasm; LES, lower esophageal sphincter; TLESR, transient lower esophageal sphincter relaxation.
Dysphagia and chest pain	Achalasia	Achalasia	Very slow	Inhibitory nerve	Thoracic esophagus LES
	DES	DES	Slow	Inhibitory nerve	Thoracic esophagus
		Hypotensive peristalsis	Slow (positional)	Inhibitory nerve Excitatory nerve Myogenic	Thoracic esophagus
Heartburn and regurgitation	GERD	TLESR	Reflux	Inhibitory nerve	LES
		Hypotensive LES	Reflux	Inhibitory nerve Excitatory nerve Myogenic	LES
		Decreased reflex contract of LES	Reflux	Excitatory nerve Myogenic	LES
		Hypotensive peristalsis	Slow (positional)	Inhibitory nerve Excitatory nerve Myogenic	Thoracic esophagus
Chest pain (?dysphagia)		Hypertensive peristalsis (nutcracker esophagus)	Normal	Excitatory nerve	Thoracic esophagus
		Hypertensive LES	Normal	Excitatory nerve	LES
		Hypercontracting LES	Normal	Excitatory nerve	LES