About the Editors
Professor Sobha Sivaprasad
Dr Sivaprasad is a Consultant Ophthalmologist at NIHR Moorfields Biomedical Research Centre, London, UK. She completed her Medical Retina Fellowship from Moorfields Eye Hospital. Her higher research degree from Cranfield University and King's College Hospital is on ‘Co-morbidity of age related macular degeneration and atherosclerosis’.
Dr Sivaprasad has active clinical and laboratory research interests in age related macular degeneration, diabetic retinopathy and retinal vascular disorders. Her research focuses on biomarkers and modeling of retinal morphology in retinal diseases.
She also runs several clinical trials in these areas and has over 100 peer reviewed publications to her credit.
Tim Aung, Singapore
MBBS (Singapore), FRCS(Ed), FRCOphth (UK), MMed (Ophth) (Singapore), FAM (Singapore), PhD (London)
Professor Aung is currently:
1. Executive Director, Singapore Eye Research Institute;
2. Deputy Medical Director (Research) and Head, Glaucoma Department, Singapore National Eye Centre;
3. Professor, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore
Professor Aung is a clinician scientist, with clinical practice focusing on glaucoma and research interests in angle closure glaucoma and glaucoma genetics. With >450 publications, Professor Aung has been awarded >US$20 million in competitive research grant funding. He has received numerous awards including the Singapore Translational Research (STaR) Investigator Award in 2014, the Singapore National Medical Research Council-Clinician Scientist Awards in 2005 and 2008, the President's Science Award in 2009, the Nakajima (2007) and De Campo Awards (2013) from the Asia Pacific Academy of Ophthalmology and the Alcon Research Institute Award in 2013.
Professor Aung is a member of the Editorial Boards of Ophthalmology, Journal of Glaucoma, Eye, Graefe's Archive for Clinical and Experimental Ophthalmology, and 6 other journals. He is currently President of the World Glaucoma Association and also serves as a Board member of the Asia-Pacific Glaucoma Society and the Asian Angle Closure Glaucoma Club.
Christopher Brand, UK
David G Charteris, UK
David F Garway-Heath, UK
Ted Garway-Heath is IGA Professor of Ophthalmology for Glaucoma and Allied Studies, and Glaucoma Theme Leader at the Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK. He serves as Vice-President to the Imaging and Perimetry Society (IPS) and is Executive Member of the Glaucoma Research Society (GRS). An important aspect of his research is the development of new tools that allow for an early detection of glaucoma. The Moorfields Motion Displacement Test, a new visual field test developed under his direction, was conferred the Overall Translational Research Innovation Award encompassing all medical fields by the UK Medical Research Council in 2008. Professor Garway-Heath is also dedicated to research in imaging techniques for the detection and monitoring of abnormalities in the optic nerve head (ONH). The Moorfields Regression Analysis, a software programme that he developed for the Heidelberg Retina Tomograph is now being used worldwide and has become a 'reference standard' for establishing the performance of other imaging devices. He is also the inventor of the structure-function correlation map (‘Garway-Heath Map’), which is being used widely in research aiming at establsihing the correlation between visual field and ONH changes, and helps the clinical evaluation of glaucoma patients and glaucoma ‘suspects’. Ted Garway-Heath is also the Principal Investigator of the UK Glaucoma Treatment Study, a landmark multicentre clinical trial investigating the effectiveness of IOP-lowering therapy in reducing the frequency of progression events compared with placebo-treated eyes, and to identify risk factors for progressive glaucoma. He is on the editorial board of several international peer-reviewed journals and has authored numerous book chapters and peer-reviewed papers.
John Heckenlively, USA
John R Heckenlively, MD, is Paul R. Lichter Professor of Ophthalmic Genetics and Professor of Ophthalmology and Visual Sciences at the University of Michigan Department of Ophthalmology. He also directs the Retinal and Macular Degenerations Center. Dr Heckenlively came to the Kellogg Eye Center in 2004 from his positions as the Chair of the Vision Genetic Center, and Director of the Visual Physiology Laboratory, Jules Stein Eye Institute, UCLA, where he held the Vernon O. Underwood Family Chair of Ophthalmology at UCLA. Dr Heckenlively earned his medical degree from the University of Coloradoand completed his residency at the University of Kentucky. He then completed two fellowships, first, in vitreoretinal diseases at the UCLA School of Medicine, Jules Stein Eye Institute; and second, in ophthalmic genetics at Johns Hopkins Hospital, Wilmer Ophthalmologic Institute and Moore Clinic.
Dr Heckenlively diagnoses and manages retinal diseases and conditions, and conducts extensive research in hereditary retinal disorders and autoimmune retinopathies. He has made significant contributions to the study of clinical retinal degenerations, ophthalmic genetics, retinal electrophysiology and research in mouse models of human eye disease. His primary aim is to establish a molecular diagnosis for all patients with inherited diseases, and to provide his patients with on-going research that will better elucidate their disease process.
Dr Heckenlively has published widely in the scientific literature, having written over 250 articles and chapters, and five textbooks. He was the founding editor for the Documenta Ophthalmologica ISCEV electrophysiology journal, and has served as a reviewer for most major ophthalmology journals, as well as for Genomics, Nature Genetics, the New England Journal of Medicine, and PNAS. The National Eye Institute funded his mouse models research continuously for the past 20 years.
Dr Heckenlively has received the Distinguished Senior Scientist Award and the Clinician-Scientist Award from Research to Prevent Blindness (1995, 2000); and the RP International, Jules Stein Living Tribute Award, 1986. He also was named a Fellow of the Royal College of Ophthalmologists in London in 1988, and elected to the American Ophthalmological Society in 1987. He was appointed an Associate Editor of Eye in 2007.
Parwez Hossain, UK
Parwez Hossain is Associate Professor in Ophthalmology at the University of Southampton & Consultant Ophthalmologist at Eye Unit, University Hospitals NHS Foundation Trust.
Parwez qualified in Medicine from Aberdeen University and trained in Ophthalmology in Aberdeen, Nottingham, Leicester & Bascom Palmer Eye Institute, Miami, USA. He sub-specializes in Cornea & External Eye Disease, and is head of the corneal service for the Southampton Eye Unit, Southampton University Hospital NHS Foundation Trust, takes care of a diverse range of corneal diseases with patients coming from different regions of the UK.
Parwez's clinician-scientist career started as Wellcome Trust Fellow at Aberdeen University where he studied the mechanisms of lymphocyte traffic in ocular inflammation. In his PhD thesis, he established a novel method for in vivo tracking of immune cells in the posterior segment of the eye. The technique allowed the observation of lymphocytes and inflamed vascular endothelium, in real-time.
Following his PhD, Parwez moved to Nottingham University, where, as a Clinical Lecturer, his interest focused on investigating the innate immune mechanisms in corneal inflammation. He determined that the immune adhesion molecule CD34 is a unique marker for human corneal stromal keratocytes (corneal fibroblast) activation. Whilst at Nottingham, he also helped to establish the effectiveness of a new surgical technique called 'Fine Needle Diathermy' to treat long standing corneal vascularization. This treatment helps against chronic corneal vascularization and can restore vision in patients with vascularisation from herpes keratitis or chronic corneal graft rejection. The technique has been adopted around the world and been validated by many centres Parwez also developed techniques in corneal confocal imaging and his work has highlighted the benefit of this in the early detection of diabetic peripheral neuropathy (published in The Lancet).
After his fellowship training period, Parwez moved to Southampton, to start a research programme in corneal infection. In his current role as Associate Professor, he leads a corneal infection research group comprising a post-doctoral fellow, PhD & undergraduate research students. His research focus is to develop new diagnostic techniques for the rapid diagnosis and monitoring of corneal infections. His group have developed technologies such as anterior segment OCT & microfluidic impedance cytometry to allow rapid microbial diagnostic detection/ monitoring. In addition, Parwez has completed several multi-centre trials to treat corneal inflammatory diseases, including novel therapy for corneal neuropathy.
With collaboration with his surgical colleagues in Southampton, Parwez has developed an active surgical research programmewith the aim to develop optimal surgical methods for corneal diseases. Developing methodssuch as ultrathin DSEK and accelerated protocols for collagen cross-linking for Keratoconus.His surgical team are part of the UK Collagen Cross-linking Consortium and are major providers for collagen crosslinking therapy for the South Coast of the UK.
Parwez has been supported by research grants from the Royal College of Surgeons of Edinburgh, the British Council for the Prevention for Blindness, EPSRC and National Eye Research Centre.
Andrew Lee, USA
Andrew G Lee, M.D. is an honors graduate of the University of Virginia undergraduate school and an Alpha Omega Alpha graduate of the UVA School of Medicine. He completed his ophthalmology residency and was the chief resident at Baylor College of Medicine in Houston, Texas in 1993. Following eye residency, Dr Lee completed a clinical fellowship in neuro-ophthalmology with Neil R. Miller MD at the Wilmer Eye Institute and was a post-doctoral Fight for Sight research fellow at the Johns Hopkins Hospital in Baltimore, Maryland from 1993-1994. He was an Associate Professor at Baylor College of Medicine and Adjunct Associate Professor at the M.D. Anderson Cancer Center in Houston from 1994-2000. From 2000-2008, Dr Lee was Professor of Ophthalmology, Neurology, and Neurosurgery in the H. Stanley Thompson Neuro-ophthalmology Clinic at the University of Iowa Hospitals and Clinics. In April 2009 Dr Lee assumed the chairmanship of ophthalmology at The Blanton Eye Institute, at Houston Methodist Hospital in Texas and was appointed Professor of Ophthalmology, Neurological Surgery and Neurology at Weill Cornell Medical College.
Dr Lee has published over 260 peer-reviewed articles, 40 book chapters, and three full textbooks in ophthalmology. He serves on the Editorial Board of 12 journals including the American Journal of Ophthalmology, the Canadian Journal of Ophthalmology, and Eye. He has received the American Academy of Ophthalmology (AAO) Honor Award, the AAO Secretariat Award, and the AAO Senior Achievement Award. Dr Lee has been the invited guest speaker at over 140 national and international eye meetings.
Dr Lee’s area of research interest is in optic nerve disease. He was the Director of New Educational Initiatives in the Graduate Medical Education (GME) office at Iowa and has published extensively in the area of resident graduate medical education. In April 2009 Dr Lee assumed the chairmanship of ophthalmology at The Methodist Hospital in Houston, Texas and was appointed Professor of Ophthalmology, Neurological Surgery and Neurology at Weill Cornell Medical College.
Caroline J MacEwen, UK
Caroline (Carrie) MacEwen is a Consultant Ophthalmologist at Ninewells Hospital and Medical School and Head of the Ophthalmology Department at the University of Dundee (Honorary Professor). She trained in Glasgow, Dundee and London. Her clinical interests lie in the field of strabismus and ocular motility after carrying out her subspecialty training at Moorfields Eye Hospital under the guidance of John Lee. Research interests include paediatric naso-lacrimal disease, trauma, sports medicine, epidemiology and clinical research on strabismus management. She has been a member of the British Ophthalmic Surveillance Unit (BOSU) committee since its inception. International and national awards for her work include the Gregg medal for ‘contribution to medical science’, the Founder's Cup, Ian Fraser trophy, Spencer Walker prize and Foulds' trophy. She has published more than 130 papers, written or edited 3 textbooks and written 17 book chapters. Carrie is an associate postgraduate Dean in the East of Scotland. She is President of the Royal College of Ophthalmologists (2014 – 2017). She represented the RCOphth in the development of the Faculty of Sport and Exercise Medicine (FSEM) and was a member of the founding council and the first chair of the faculty’s examination committee.
Hunter MacLean, UK
Hunter Maclean is a Consultant Ophthalmologist at the Queen Alexandra Eye Hospital Portsmouth, in the south of England. He specialises in oculoplastics and lacrimal surgery. He received his medical degree from Edinburgh University and did further training there and at Newcastle with a fellowship in Sydney, Australia before taking up his consultant post in 1998. He was a founding member of the British Oculoplastic surgical society and takes an active part in research within the department and is also the current President of the Southern Ophthalmological Society. He has written one book and contributed several chapters in others. He was appointed Associate Editor of Eye in 2009.
Rupal H Trivedi, USA
Dr Trivedi is a Research Associate Professor at Storm Eye Institute, Medical University of South Carolina, USA. She completed her residency in Ophthalmology from India in 1995. From 1995 to 2000, she worked at Iladevi cataract and IOL research center, India. She received her Master of Science in Clinical Research (MSCR) degree from Medical University of South Carolina. Dr Trivedi's research interests include cataract surgery, especially for children. She has published more than 100 articles in peer-reviewed journals and presented her research work at various national and international meetings. She is recipient of various awards including ASCRS foundation Binkhorst young ophthalmologist award, American Academy of Ophthalmology Achievement Award, RCMAR scholar award and Clinical Research Curriculum Award.
Steve Beet, UK