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Relation between food intake and visual analogue scale ratings of appetite and other sensations in healthy older and young subjects

European Journal of Clinical Nutrition volume 58, pages 212–218 (2004)Cite this article

Abstract

Objective: Visual analogue scales are widely used in appetite research, yet the validity of these scales to evaluate appetite and mood has not been assessed in older subjects. The aim of this study was to determine the relations between food intake and visual analogue scale (VAS) ratings of appetite and nonappetite sensations in healthy older and young subjects.

Design: Retrospective combined analysis of four single-blind, randomised, controlled appetite studies.

Setting: All studies were conducted in the University of Adelaide, Department of Medicine, Adelaide, Australia.

Subjects: A total of 45 healthy young men (n=24) and women (n=21) aged 18–35 y and 45 healthy older men (n=24) and women (n=21) aged 65–85 y were recruited by advertisement.

Interventions: Oral, intraduodenal or intravenous administration of treatments which suppressed food intake were compared to control. Up to 90 min after treatment, a test meal was offered and subjects ate freely for between 30 and 60 min. Perceptions were assessed by 100-mm visual analogue scales administered at regular intervals.

Results: Food intake at the test meal was positively related to perceptions of hunger, drowsiness, and calmness at both baseline and premeal (r>0.16, P<0.05), and inversely related to premeal ratings of fullness (r> 0.2, P<0.05) in both older and young subjects. Food intake was related to VAS ratings at least as strongly, if not more so, in older as in young subjects.

Conclusions: These observations (i) confirm that food intake is related to perceptions of hunger and fullness as assessed by VAS in healthy older and young subjects, and (ii) suggest that sensations, not obviously associated with appetite, including ‘drowsiness’ and ‘calmness’, are also associated with food intake.

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References

  • Andrews JM, Doran SM, Hebbard GS, Rassias G, Sun WM & Horowitz M (1998): Effect of glucose supplementation on appetite and the pyloric motor response to intraduodenal glucose and lipid. Am. J. Physiol. 274, G645–G652.

    Article  CAS  Google Scholar 

  • Christensen L (1993): Effects of eating behaviour on mood: a review of the literature. Int. J. Eat. Disord. 14, 171–183.

    Article  CAS  Google Scholar 

  • Clarkston WK, Pantano MM, Morley JE, Horowitz M, Littlefield JM & Burton FR (1997): Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly versus young adults. Am. J. Physiol. 272, R243–R248.

    CAS  PubMed  Google Scholar 

  • Cook CG, Andrews JM, Jones KL, Wittert GA, Chapman IM, Morley JE & Horowitz M (1997): Effects of small intestinal nutrient infusion on appetite and pyloric motility are modified by age. Am. J. Physiol. 273:R755–R761.

    Article  CAS  Google Scholar 

  • de Castro JM (1987): Macronutrient relationships with meal patterns and mood in the spontaneous feeding behavior of humans. Physiol. Behav. 39, 561–569.

    Article  CAS  Google Scholar 

  • Flint A, Raben A, Blundell JE & Astrup A (2000): Reproducibility, power, and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int. J. Obes. Relat. Metab. Disord. 24, 38–48.

    Article  CAS  Google Scholar 

  • Folstein MF, Folstein S & McHuth PR (1975): Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12, 189–198.

    Article  CAS  Google Scholar 

  • Fried LP, Kronmal RA, Newman AB, Bild DE, Mittelmark MB, Polak JF, Robbins JA & Gardin JM (1998): Risk factors for 5-year mortality in older adults. The cardiovascular health study. JAMA 279, 585–592.

    Article  CAS  Google Scholar 

  • Horowitz M, Maddern GJ, Chatterton BE, Collins PJ, Harding PE & Shearman PJ (1984): Changes in gastric emptying rates with age. Clin. Sci. 67, 213–218.

    Article  CAS  Google Scholar 

  • Kopelman PG (2000): Obesity as a medical problem. Nature 404, 635–643.

    Article  CAS  Google Scholar 

  • Lavin J, Wittert G, Sun W-M, Horowitz M, Morley JE & Read N (1996): Appetite regulation by carbohydrate: role of blood glucose and gastrointestinal hormones. Am. J. Physiol. 271, E209–E214.

    CAS  PubMed  Google Scholar 

  • MacIntosh CG, Horowitz M, Verhagen M, Smout A, Wishart J, Morris H, Goble E, Morley JE & Chapman IM (2001a): Effect of small intestinal nutrient infusion on appetite, gastrointestinal hormone release and gastric myoelectrical activity in young and older men. Am. J. Gastroenterol. 96, 997–1007.

    Article  CAS  Google Scholar 

  • MacIntosh CG, Sheehan J, Davani N, Morley JE, Horowitz M & Chapman IM (2001b): Effects of aging on the opioid modulation of feeding in humans. J. Am. Geriatr. Soc. 49, 1518–1524.

    Article  CAS  Google Scholar 

  • MacIntosh CG, Morley JE, Wishart J, Morris H, Jansen JB, Horowitz M & Chapman IM (2001c): Effect of exogenous cholecystokinin (CCK)-8 on food intake and plasma CCK, leptin, and insulin concentrations in older and young adults: evidence for increased CCK activity as a cause of the anorexia of aging. J. Clin. Endocrinol. Metab. 86, 5830–5837.

    Article  CAS  Google Scholar 

  • Mattes R (1990): Hunger ratings are not a valid proxy measure of reported food intake in humans. Appetite 15, 103–113.

    Article  CAS  Google Scholar 

  • Morley JE & Silver AJ (1998): Anorexia in the elderly. Neurbiol. Aging 9, 9–16.

    Article  Google Scholar 

  • Morley JE (1997): Anorexia of aging: physiologic and pathologic. Am. J. Clin. Nutr. 66, 760–773.

    Article  CAS  Google Scholar 

  • Mowe M, Bohmer T & Kindt E (1994): Reduced nutritional status in an elderly population (&gt;70) is probable before disease and possibly contributes to the development of disease. Am. J. Clin. Nutr. 59, 317–324.

    Article  CAS  Google Scholar 

  • Patel KA & Schlundt DG (2001): Impact of moods and social context on eating behaviour. Appetite 36, 111–118.

    Article  CAS  Google Scholar 

  • Raben A, Tagliabue A & Astrup A (1995): The reproducibility of subjective appetite scores. Br. J. Nutr. 73, 517–530.

    Article  CAS  Google Scholar 

  • Rayner CK, MacIntosh CG, Chapman IM, Morley JE & Horowitz M (2000): Effects of age on proximal gastric motor and sensory function. Scand. J. Gastroenterol. 35, 1041–1047.

    Article  CAS  Google Scholar 

  • Rolls BJ (1992): Aging and appetite. Nutr. Rev. 50, 422–426.

    Article  CAS  Google Scholar 

  • Rolls BJ, Dimeo KA & Shide DJ (1995): Age-related impairments in the regulation of food intake. Am. J. Clin. Nutr. 62, 923–931.

    Article  CAS  Google Scholar 

  • Sepple CP & Read NW (1989): Gastrointestinal correlates of the development of hunger in man. Appetite 13, 183–191.

    Article  CAS  Google Scholar 

  • Stubbs RJ, Hughes DA, Johnstone AM, Rowley E, Reid C, Elia M, Stratton R, Delargy H, King N & Blundell JE (2000): The use of visual analogue scales to assess motivation to eat in human subjects: a review of their reliability and validity with an evaluation of new hand-held computerized systems for temporal tracking of appetite ratings. Br. J. Nutr. 4, 405–415.

    Article  Google Scholar 

  • Stunkard AJ & Messick S (1985): The three factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J. Psychosom. Res. 29, 71–83.

    Article  CAS  Google Scholar 

  • Sturm K, MacIntosh CG, Parker B, Wishart J, Horowitz M & Chapman I (2002): Effect of age and nutritional status on food intake and plasma cholecystokinin; evidence for reduced hunger rather than increased satiety as a cause of the anorexia of aging. Gastroenterology 122 (Suppl), A-68.

    Google Scholar 

  • Sun WM, Doran S, Jones KL, Ooi E, Boeckxstaens G, Hebbard GS Lingenfelser T, Morley JE, Dent J & Horowitz M (1998): Effects of nitroglycerin on liquid gastric emptying and antropyloroduodenal motility. Am. J. Physiol. 275(part 1), G1173–G1178.

    CAS  PubMed  Google Scholar 

  • Wells AS & Read NW (1995): Influences of dietary and intraduodenal lipid on alertness, mood, and sustained concentration. Br. J. Nutr. 74, 115–123.

    Article  CAS  Google Scholar 

  • Wells AS, Read NW, Uvnas-Moberg K & Alster P (1997): Influences of fat and carbohydrate on postprandial sleepiness, mood and hormones. Physiol. Behav. 61, 679–686.

    Article  CAS  Google Scholar 

  • Wurtman JJ, Lieberman H, Tsay R, Nader T & Chew B (1988): Calorie and nutrient intakes of elderly and young subjects measured under identical conditions. J. Gerontol. 43, B174–B180.

    Article  CAS  Google Scholar 

  • Yesavage JA (1998): Geriatric Depression Scale. Psychopharmacol. Bull. 24, 709–710.

    Google Scholar 

Download references

Acknowledgements

This work was supported by a project grant of the National Health and Medical Research Council (NH&MRC) of Australia to Dr I Chapman, an Australian Postgraduate Award scholarship to Ms B Parker, a Royal Adelaide Hospital Dawes Research Fellowship to Dr C MacIntosh and a Australian–German Joint Research Cooperation Scheme scholarship from Deutscher Akademischer Austausch Dienst for Dr K Sturm.

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  1. Department of Medicine, University of Adelaide, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia

    B A Parker, K Sturm, C G MacIntosh, C Feinle, M Horowitz & I M Chapman

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  1. B A Parker
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Parker, B., Sturm, K., MacIntosh, C. et al. Relation between food intake and visual analogue scale ratings of appetite and other sensations in healthy older and young subjects. Eur J Clin Nutr 58, 212–218 (2004). https://doi.org/10.1038/sj.ejcn.1601768

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