Spiralling electron beams have the potential to measure and manipulate the properties of single atoms.
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References
Verbeeck, J., Tian, H. & Schattschneider, P. Nature 467, 301-304 (2010).
Uchida, M. & Tonomura, A. Nature 464, 737-739 (2010).
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Merali, Z. Electron microscopy gets twisted. Nature (2010). https://doi.org/10.1038/news.2010.468
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DOI: https://doi.org/10.1038/news.2010.468