The ability to become nearly any cell type is restricted to eggs, sperm and primitive stem cells in very early embryos. Two studies reveal that maintaining this pluripotent state in vitro comes at a cost. See Letters p.219 & p.224
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Zwaka, T. The cost of perpetual youth. Nature 548, 165–166 (2017). https://doi.org/10.1038/nature23102
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DOI: https://doi.org/10.1038/nature23102