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Volume 32 Issue 5, May 2022

The image describes an ancient Chinese myth “Hou Yi Shoots the Suns”, wherein Hou Yi was tasked to save people by shooting nine extra buring suns. Voltage-gated H+ channel Hv1 was unexpectedly identified in the sensory neurons; inhibiting neuroinflammation (symbolized by the burning suns) by targeting Hv1 genetically or pharmacologically using a newly-discovered inhibitor (symbolized by arrow) alleviates chronic inflammatory pain and morphine-induced adverse side effects. The cover art is contributed by Keyu Yu. See page 461–476 by Qiansen Zhang et al. for details.

Volume 32 Issue 5

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