Volume 31 Issue 8, August 2021

SARS-CoV-2 envelope protein (2-E) attacks host cells offensively via forming a type of cation channels on biological membranes. The newly identified channel blocker BE-33 exhibits excellent anti-viral activity in mice infection model. 2-E channel is a promising drug target against SARS-CoV-2.See page 847-860 by Bingqing Xia et al. for details.

Research Highlight

SARS-CoV-2 vaccines: anamnestic response in previously infected recipients

Jyothi N. Purushotham
Neeltje van Doremalen
Vincent J. Munster
Research Highlight 18 May 2021
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Nascent RNA m⁶A modification at the heart of the gene–retrotransposon conflict

Victor Billon
Gael Cristofari
Research Highlight 09 Jun 2021
Host genetics, the microbiome & behaviour—a ‘Holobiont’ perspective

Jatin Nagpal
John F. Cryan
Research Highlight 14 May 2021
Pancreatic endocrinogenesis revisited: “I have all the answers, who has the questions?”

Willem Staels
Raphael Scharfmann
Research Highlight 10 Mar 2021

Top of page ⤴

Article

A cohort autopsy study defines COVID-19 systemic pathogenesis

Xiao-Hong Yao
Tao Luo
Xiu-Wu Bian

Collection:

Editor’s selections: top articles from the past 3 years
Article Open Access 16 Jun 2021
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target

Bingqing Xia
Xurui Shen
Zhaobing Gao

Collection:

Editor’s selections: top articles from the past 3 years
Article Open Access 10 Jun 2021
RNA m⁶A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability

Feng Xiong
Ruoyu Wang
Wenbo Li

Collection:

Editor’s selections: top articles from the past 3 years
Article Open Access 09 Jun 2021
Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans

Xin-Xin Yu
Wei-Lin Qiu
Cheng-Ran Xu
Article 10 Mar 2021
Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain

Kaikai Wang
Sashuang Wang
Xu Zhang
Article 10 Mar 2021
Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study

Cheng Wang
Hong Lv
Zhibin Hu
Article 09 Jun 2021

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Letter to the Editor

Molecular basis of ligand recognition and activation of human V2 vasopressin receptor

Fulai Zhou
Chenyu Ye
Yi Jiang
Letter to the Editor 19 Mar 2021
Cryo-EM structure of the AVP–vasopressin receptor 2–G_s signaling complex

Lei Wang
Jun Xu
Cheng Zhang
Letter to the Editor 04 Mar 2021
Sulfated glycosaminoglycans and low-density lipoprotein receptor mediate the cellular entry of Clostridium novyi alpha-toxin

Yao Zhou
Diyin Li
Liang Tao
Letter to the Editor Open Access 10 May 2021

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Correction

Publisher Correction: Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain

Kaikai Wang
Sashuang Wang
Xu Zhang
Correction 19 May 2021
Author Correction: Cryo-EM structures of the full-length human KCC2 and KCC3 cation-chloride cotransporters

Ximin Chi
Xiaorong Li
Qiang Zhou
Correction 15 Jul 2021

Top of page ⤴

Volume 31 Issue 8, August 2021

Research Highlight

SARS-CoV-2 vaccines: anamnestic response in previously infected recipients

Nascent RNA m⁶A modification at the heart of the gene–retrotransposon conflict

Host genetics, the microbiome & behaviour—a ‘Holobiont’ perspective

Pancreatic endocrinogenesis revisited: “I have all the answers, who has the questions?”

Article

A cohort autopsy study defines COVID-19 systemic pathogenesis

SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target

RNA m⁶A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability

Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans

Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain

Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study

Letter to the Editor

Molecular basis of ligand recognition and activation of human V2 vasopressin receptor

Cryo-EM structure of the AVP–vasopressin receptor 2–G_s signaling complex

Sulfated glycosaminoglycans and low-density lipoprotein receptor mediate the cellular entry of Clostridium novyi alpha-toxin

Correction

Publisher Correction: Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain

Author Correction: Cryo-EM structures of the full-length human KCC2 and KCC3 cation-chloride cotransporters

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