Volume 29 Issue 6, June 2019

An old saying from the ancient Chinese philosopher Zhuangzi (Zhuang-Tzu), “A frog in bottom of well doth not imagine sea, whilst an insect in summer doth not interpret ice”, can illustrate that hierarchical activation of AMPK is a matter of space and time. See page 460-473 by Yue Zong et al. for details.