Volume 28 Issue 5, May 2018

Clinical anti-mitotic drugs induce Death receptor 3 (DR3) - mediated apoptosis in cancer cells. The expression of DR3 or its ligand TL1A corresponds to the apoptotic response, thus may hold promise to be used as predicting biomarkers for clinical response to anti-mitotic therapeutics. See page 544–555 by Chen Qi et al. for details.