• Schematic of nucleic acids in a double helix

    We are currently welcoming submissions to a number of open Collections, including:

    * Batteries under extreme conditions

    * Supramolecular polymers

    * Fluorescent probes for bioimaging and biosensing

    * Nucleic acid chemistry

  • Multicoloured image of head silhouettes

    Interested in joining our editorial board and helping to shape our journal and the manuscripts that we publish in your areas of research? Please fill in our Google form (link above) to indicate your interest. We are particularly interested in hearing from women and those with other underrepresented identities.

  • Prof Doory Kim's headshot

    In July, we thank Prof Doory Kim for her invaluable contributions to peer review. Her current research focuses on the development and application of new super-resolution microscopic and spectroscopic techniques for chemical and biological research.


  • ATP-binding cassette transporter ABCB1 is known to be involved in drug resistance in cancer treatment, however, current ABCB1 inhibitors have not been successful in clinical trials due to their potential cytotoxicity. Here, the authors hypothesize that potential ABCB1 substrates in bats could act as competitive inhibitors against ABCB1 in humans, and identify the tryptophan structure as a promising lead structure for the development of non-toxic ABCB1 inhibitors.

    • Javier Yu Peng Koh
    • Yoko Itahana
    • Koji Itahana
    ArticleOpen Access
  • Criegee intermediates such as CH2OO play an important role in tropospheric oxidation models through their reactions with atmospheric trace chemicals. Here, the authors develop a global full-dimensional potential energy surface for the CH2OO + SO2 system, reveal how the reaction happens step by step using quasi-classical trajectory simulations, to show a new direct stripping pathway forming the main products CH2O and SO3 and a new product channel.

    • Cangtao Yin
    • Gábor Czakó
    ArticleOpen Access
  • The propargyl radical (C3H3) self-reaction is a pivotal step in the formation of benzene in nature, but experimental validation for the complex reaction channels and products is challenging to obtain. Here, the authors produce propargyl radicals in a flow tube and report the branching ratios of eight identified C6H6 isomers in the propargyl self-reaction using isomer-selective threshold-photoelectron spectroscopy.

    • Helgi Rafn Hrodmarsson
    • Gustavo A. Garcia
    • Jean-Christophe Loison
    ArticleOpen Access
  • Hypervalent iodine(III) reagents show promising properties in organic synthesis, however, the application of nitrooxyl (O2NO)-containing I(III) reagents remains underexplored. Here, the authors report the synthesis of a benziodazole-type O2NO-I(III) reagent, which can be applied to the synthesis of furazan heterocycles as a nitrating agent, by reaction with β-monosubstituted enamines via a copper-catalyzed radical nitration/cyclization/dehydration cascade.

    • Zhifang Yang
    • Jun Xu
    • Yunfei Du
    ArticleOpen Access
  • Boronate-based ß-lactamase inhibitors play an important role in treating multidrug-resistant bacteria infection, however, the molecular mechanism of inhibition remains unclear. Here, the authors use time-resolved serial crystallography to investigate the binding process by using boric acid as a model against β-lactamase CTX-M-14, revealing the binding to the active site serine within 80–100 ms, a subsequent 1,2-diol boric ester formation with glycerol within 100–150 ms, as well as the displacement of the sulfate anion in the active site.

    • Andreas Prester
    • Markus Perbandt
    • Christian Betzel
    ArticleOpen Access
    • On-surface synthesis is a useful approach for the construction of nanoporous graphene materials, which are in turn of interest for various electronic applications. Here, the authors review the latest developments in the on-surface synthesis of atomically precise pristine and hetero-atom doped nanoporous graphene materials.

      • Tianchen Qin
      • Tao Wang
      • Junfa Zhu
      Review ArticleOpen Access
    • Nucleic acids are key elements in numerous applications such as therapeutics and nanotechnology. However, the synthesis of long and modified oligonucleotides remains challenging and alternative, biocatalytic approaches are needed. Here, the authors discuss recent progress in the controlled enzymatic synthesis of oligonucleotides.

      • Maëva Pichon
      • Marcel Hollenstein
      PerspectiveOpen Access
    • The electrochemical Leaf (e-Leaf) is an emerging technology that addresses complex enzyme cascades nanoconfined within a porous conducting material—exploiting efficient electron tunneling and local NADP(H) recycling to transduce catalysis and electricity. Here, the authors describe how the e-Leaf was discovered, the steps in its development so far, and the outlook for future research and applications.

      • Bhavin Siritanaratkul
      • Clare F. Megarity
      • Fraser A. Armstrong
      PerspectiveOpen Access
    • Brønsted basicity can be greatly enhanced by the mechanical entanglement of two or more interlocked molecular subunits within catenanes and rotaxanes. Here, the authors discuss the development of such mechanically interlocked superbases, and outline challenges and opportunities for future directions of research.

      • Giorgio Capocasa
      • Federico Frateloreto
      • Stefano Di Stefano
      Review ArticleOpen Access
    • Molecular complexes with single-molecule magnet or qubit properties are great candidates for quantum information storage and processing, however, device implementation requires controlled surface deposition and property retention, which is a challenge. This Perspective gives a brief overview of molecular properties on a surface relevant for magnetic molecules and how they are affected by surface deposition, pointing out possible ways of overcoming the problems encountered so far.

      • Guillem Gabarró-Riera
      • E. Carolina Sañudo
      PerspectiveOpen Access
  • Extraterrestrial carbon gives insights into the origin of life and processes that took place billions of years ago in our solar system. Here, the authors provide an overview of what is known and of unanswered questions with a meteoritical focus.

    • Oliver Christ
    • Fabrizio Nestola
    • Matteo Alvaro
    CommentOpen Access
  • Rare-earth telluride clusters enable the construction of highly crystalline rare-earth tellurides, but a general route for preparing such clusters is lacking. Now, a facile reduction approach produces rare-earth clusters supported by (poly)tellurido ligands, including a tri-tellurido ligand with a three-center, four-electron bonding structure.

    • Chenyu Wang
    Research HighlightOpen Access
  • The chemical reduction of group 1 metal cations to their zero-valent species is challenging. Now, a bipyridine-stabilized borate anion joins the ranks of suitable reducing agents and also proves active in the two-electron reduction of CO2.

    • Johannes Kreutzer
    Research HighlightOpen Access
  • FAIR (findable, accessible, interoperable and reusable) data practices are necessary to expedite knowledge discovery, encourage collaboration, and optimise resource use, fostering a robust foundation for future scientific progress. Here, the authors explore the use of FAIR practices to advance materials chemistry research, examining key repositories, highlighting their role in sharing scientific data, and examining the accessibility of these approaches.

    • Konstantin Stracke
    • Jack D. Evans
    CommentOpen Access
  • Communications Chemistry is pleased to introduce a Collection of articles focused on organomediated polymerization. Here, the Guest Editors highlight the themes within and look towards the future of this research field.

    • Satoshi Honda
    • Karin Odelius
    • Haritz Sardon
    EditorialOpen Access
Circular carbon economy

Electrocatalytic CO2 reduction

The electrochemical reduction of carbon dioxide (CO2) is a key technology to combat global climate issues. By utilizing renewable energy, we can convert greenhouse gases into value-added commodity chemicals. While there has been a growing number of CO2 research in recent years, there are still many unanswered fundamental questions and engineering challenges. With this collection, we encourage scientists from different academic backgrounds to explore these remaining challenges in the CO2 electrochemical reduction reaction and provide a forum for the CO2 community to share their latest research results. We welcome all submission of original research articles, reviews and perspectives related to the theme of CO2 electrocatalytic reduction.


Nature Careers

Science jobs