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    Would you like to learn more about Communications Chemistry, the editorial process, or the Nature Portfolio journals? Keen to discuss a manuscript, or organize a lab visit or publishing talk?

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    This month we thank Dr Yujie Chi for her invaluable contributions to peer review. Dr Yujie Chi is a medical physicist interested in modeling fundamental processes behind ionizing radiation induced biological effects and developing irradiation facilities for in-vitro irradiation studies.

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    Communications Chemistry has a 2-year impact factor of 6.581 (2021), and mean decision times of 3 days to first editorial decision and 31 days to first post-review decision (2020).

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  • Mutations to oncogenic protein KRAS are responsible for some of the deadliest cancers, and KRAS is thus a key target for new antitumour agents. Here, a short bis-histidine peptide derived from the αH helix of the cofactor SOS1 is designed and shown to reversibly bind to KRAS with high affinity upon coordination to Pd(II), inhibiting KRAS-activated pathways in live cells.

    • Soraya Learte-Aymamí
    • Pau Martin-Malpartida
    • M. Eugenio Vázquez
    Article Open Access
  • Detection of trimethylamine N-oxide (TMAO) can allow for early intervention of cardiovascular disease, but is challenging to achieve using conventional materials and instruments owing to it being spectroscopically silent in the UV-visible region. Here, a series of bilanthanide metalorganic frameworks functionalised with a borono group are shown to detect TMAO with high sensitivity and selectivity by exploiting the inverse emission intensity changes of the two lanthanide centres.

    • Hui Min
    • Zhonghang Chen
    • Peng Cheng
    Article Open Access
  • Polymer beads are used in the core of magnetic particles, and beads functionalised with paramagnetic molecules are promising as agents for dynamic nuclear polarization. Here, the authors use conventional click chemistry to decorate a polymer bead with 1014 [2]rotaxanes containing paramagnetic {Cr7Ni} rings.

    • Deepak Asthana
    • Dean Thomas
    • Richard E. P. Winpenny
    Article Open Access
  • Competition between attractive and repulsive interactions between colloidal particles drives the formation of complex assemblies. Here, the authors exploit the dual functionality of magnetic nanoparticle dispersions to simultaneously drive attraction and repulsion between suspended non-magnetic microspheres, allowing for precise tuning of the interaction energy landscape of colloidal particles.

    • Ahmed Al Harraq
    • Aubry A. Hymel
    • Bhuvnesh Bharti
    Article Open Access
  • Core-shell particles with thin noble metal shells represent an attractive material class with potential for various applications ranging from catalysis to biomedical applications, but the synthesis of well-defined core-shell architectures remains highly challenging. Here, the authors report the chemically induced self-limiting growth of atomically-thin and homogeneous platinum shells on a variety of gold nanostructures.

    • Marc Ledendecker
    • Paul Paciok
    • A. Paul Alivisatos
    Article Open Access
  • Dry reforming of methane into syngas typically requires high temperatures, which can cause aggregation and deterioration of the catalyst. Here, the authors report a lanthanum nickel oxide catalyst prepared by in situ hydrogen reduction of LaNi0.05Co0.05Cr0.9O3 on a LaCrO3 perovskite support that remains stable for over 100 h at 750 °C.

    • Tingting Zhao
    • Jiankang Zhao
    • Haiqian Wang
    Article Open Access
  • Strong emergence is the main form of emergence that has been defended with respect to chemistry, and in particular molecular structure. Here, the author spells out this form of emergence, proposes new ways in which one can further explore the question of emergence, and explains why investigating emergence should be of interest not only to philosophers but to chemists as well.

    • Vanessa A. Seifert
    Comment Open Access
  • Interfacing ultrasmall metal nanoclusters (NCs) with proteins can present a dual opportunity: proteins can be used for protecting NCs, and the surface ligands of NCs may interact with proteins. Here, the authors identify and discuss remaining open questions surrounding the bio-NC interface that call for future research efforts.

    • Rodolphe Antoine
    • Dusica Maysinger
    • Vlasta Bonačić-Koutecký
    Comment Open Access
  • Tooth enamel possesses outstanding viscoelasticity as well as stiffness — a combination of properties often considered a trade-off. Now, a bi-directional freezing method affords a biomimetic composite with mechanical properties superior to those of enamel.

    • Teresa S. Ortner
    Research Highlight Open Access
  • The cluster approach is a very valuable technique for elucidating reaction mechanisms of enzymes. Here, the authors discuss the current status of this methodology, highlighting its strengths and weaknesses, and argue that it should be the method of choice for investigating enzymatic reaction mechanisms.

    • Fahmi Himo
    • Sam P. de Visser
    Comment Open Access
  • This International Women’s Day, the editors of Communications Chemistry reflect on the responsibilities that journal editors have towards promoting gender equity in STEM, and outline some of the ways in which editors can show up for women in chemistry.

    Editorial Open Access
  • Emerging experimental techniques combined with theoretical advances allow unprecedented studies of the dynamics of gas phase molecules and clusters induced in interactions with photons, electrons, or heavy particles. Here, the authors highlight recent advances, key open questions, and challenges in this field of research with focus on experimental studies of dynamics of ions stored on millisecond timescales and beyond, and its applications in astrochemistry and astronomy.

    • Michael Gatchell
    • Henning Zettergren
    Comment Open Access
Questionmarks

Open Questions in Chemistry

In spite of decades of research and the enormous progress made, chemists continue to grapple with poorly understood aspects of the world around us. This collection aims to uncover open questions across the breadth of the chemical sciences. Each Comment provides an overview of a focused field of research, identifies key open questions, and gives expert opinion on how challenges in answering these questions might be overcome.
Collection
Open for submissions

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