A GWAS study reveals that genes related to occupational creativity are associated with both positive and negative well-being variables, positively correlate with career success, and negatively correlate with reproductive success

The cell surface receptor TIM-3 mediates an inflammatory response in myeloid cells within mouse lungs via galectin-3.

A long-term survey on the reproductive strategy of the stony coral, Fimbriaphyllia (Euphyllia) ancora, found that the majority of the colonies change their sex every year.

Enrichment and analysis of regulatory-active chromatin cfDNA fragments in blood offer a non-invasive method for monitoring dynamic changes in epigenetic and gene expression patterns, underscoring its potential utility in precision medicine.

Intracranial EEG recordings of the default mode and dorsal attention networks show robust (de)activation patterns, especially in the low-frequency (> 30 Hz) power, with direction of the information flow from the activated to the deactivated network.

Environmental stress on coral reefs is increasing. Authors show a stress-related reduction in residency of grey reef sharks on the remote reefs of the Chagos Archipelago, promoting more diffuse space use and increased time away from the shallow forereefs.

Carvacrol activates mouse OTOP1 (mOTOP1) at neutral and acidic pH, but not other OTOPs. Key residues S134 and T247 are critical for carvacrol sensitivity, highlighting TM3 and TM5-6 linker as crucial for gating and drug design.

MMAPLE, a semi-supervised meta-learning framework, effectively addresses data scarcity and out-of-distribution challenges in deep learning. It uncovers novel drug-target, metabolite-enzyme, and microbiome-human interactions.

An ancestry-specific and trans-ethnic meta-analysis of Genome-wide Association Study of blood NfL levels identified multiple loci related to neurodegeneration and potential causal association between reduced kidney function and higher blood NfL levels.

Modeling and data show that marmoset monkeys use active sensing to acquire social information from conspecifics; this challenges traditional views of primate communication.

Introductory sentence: In this Q&A, Brianna Bibel, also known as the Bumbling Biochemist, talks to the journal about how social media can be harnessed to relay scientific information to other researchers, while making it fun and accessible.

Conducting research at the interface of chemistry, microbiology and marine biology, Constanze Kuhlisch reports on challenges in science due to COVID and the situation in Israel, while preparing grants to start her own research group.

Embracing the underlying principles and processes of informed proxy consent or relational autonomy consent in human ancient DNA research can transform research.

This comment reports on work done at Harvard Medical School to identify areas for improvement in research rigor, reproducibility, and responsibility in pursuit of continued research excellence.

Documentation of women’s inclusion in Indian academia and conferences by BiasWatchIndia reveals the scale of underrepresentation of women across science, technology, engineering and mathematics.