A GWAS study reveals that genes related to occupational creativity are associated with both positive and negative well-being variables, positively correlate with career success, and negatively correlate with reproductive success

The cell surface receptor TIM-3 mediates an inflammatory response in myeloid cells within mouse lungs via galectin-3.

A long-term survey on the reproductive strategy of the stony coral, Fimbriaphyllia (Euphyllia) ancora, found that the majority of the colonies change their sex every year.

Enrichment and analysis of regulatory-active chromatin cfDNA fragments in blood offer a non-invasive method for monitoring dynamic changes in epigenetic and gene expression patterns, underscoring its potential utility in precision medicine.

Formation of biomolecular condensate via liquid-like assembly of PARylated PARP1 is driven by biogenic cations. This assembly regulates autoPARylation of PARP1, PARG-dependent hydrolysis of poly(ADP-ribose) and Polβ-mediated DNA synthesis.

204 Macrocystis pyrifera genotypes were screened and a panel of heat-stress tolerant (HST) gametophytes were identified. A subsequent analysis revealed a correlation between the HST strains and increased sporophyte biomass under warmer ocean conditions.

Collagen-binding protein (Cnm), a surface protein possessed by Streptococcus mutans, is a possible pathogenic factor in IgA nephropathy development, as IgA nephropathy-like nephritis was induced in rats following Cnm administration.

Sexual behavior among men who have receptive anal intercourse with men is linked to changes in the gut microbiome and systemic inflammation leading to HIV-1 infection.

A study to develop an optogenetic model of tau aggregation provides proof-of-concept for utilization of optoTAU to investigate the consequences of tau aggregation in human neurons and identify modifiers of tau aggregation in tauopathies.

Mice lacking TUBB4B are profoundly deaf due to defects in both the middle and inner ear consisting in microtubule alterations in cochlear supporting cells and motile cilia defects in epithelial cells.

In this Q&A, Brianna Bibel, also known as the Bumbling Biochemist, talks to the journal about how social media can be harnessed to relay scientific information to other researchers, while making it fun and accessible.

Conducting research at the interface of chemistry, microbiology and marine biology, Constanze Kuhlisch reports on challenges in science due to COVID and the situation in Israel, while preparing grants to start her own research group.

Embracing the underlying principles and processes of informed proxy consent or relational autonomy consent in human ancient DNA research can transform research.

This comment reports on work done at Harvard Medical School to identify areas for improvement in research rigor, reproducibility, and responsibility in pursuit of continued research excellence.

Documentation of women’s inclusion in Indian academia and conferences by BiasWatchIndia reveals the scale of underrepresentation of women across science, technology, engineering and mathematics.