A review of citation rates from genomic studies in the GWAS Catalog suggests that sharing summary statistics results, on average, in ~81.8% more citations, highlighting a benefit of publicly sharing GWAS summary statistics.

Multi-omic and evolutionary analyses of the ultrasmall green algae, Medakomo hakoo, suggest that it might belong to a new genus within the class Trebouxiophyceae and provide further insight into the essential genes for microalgae.

A cell-based assay for detecting SNAP25-cleaving Botulinum neurotoxins (BoNTs) is developed by combining hiPSC-derived motor neurons and a luminescent detection system based on split NanoLuc luciferase.

A genomic investigation into strains of the plant pathogen, Xylella fastidiosa, in France indicate an American origin with two waves of invasion.

In a breast cancer cell line migrating through microchannels, stress-responsive paraspeckle numbers increase under confinement and polarize towards the leading edge.

A genome-wide association study in the BioBank Japan cohort reveals new locus, BET1L, which is associated with survival time in a Japanese population.

A new method, named array fluorescent micro-optical sectioning tomography (array-fMOST), is developed for identifying the three-dimensional information at single-cell resolution from multi-samples.

Multivariate neuroimaging analyses of participants in a texture discrimination task suggests that cognitive fatigue via repeated stimulus exposure impacts the activity of task-relevant networks and is associated with tangible behavioral repercussions.

Analyses of colouration, head shape, and genetic markers across pairs of neighbouring beach and inland habitats reveal replicated patterns of morphological divergence in the Madeiran wall lizard, despite gene flow between habitats.

Molecular dynamics simulations of multidrug resistance protein 1 (MRP1) with varying membrane composition suggest that the composition has limited impact on the structures, but rather affects the conformational transitions and kinetics of substrate transport.

A review of citation rates from genomic studies in the GWAS Catalog suggests that sharing summary statistics results, on average, in ~81.8% more citations, highlighting a benefit of publicly sharing GWAS summary statistics.

Cilia assembly and function require intraflagellar transport (IFT), a mechanism that uses “trains” to transport cargoes into and out of cilia. While much has been learned about IFT in the past decades, IFT train assembly, loading of cargo and transport regulation have remained poorly understood. In a recent study, Hesketh, Mukhopadhyay and colleagues obtained the complete structure of the IFT-A complex, a key element of IFT trains. By modelling IFT-A into anterograde trains and performing structure-guided mutagenesis, the authors uncover how the IFT-A complex polymerizes and forms carriages to accomplish its distinctive functions.

We reflect on how far we have come while looking forward to the next phase of our journey.

Recent structures of DNA-bound bacterial and phage recombinases provide insights into homologous recombination and suggest relation to the eukaryotic Rad52 and identification of a Rad52 single strand annealing protein (SSAP) superfamily.

The BIL1/BZR1 transcription factor is known to regulate transcriptional responses to the brassinosteroid class of phytohormones by directly recognizing short cis regulatory elements in promoters. A new study by Shohei Nosaki, Nobutaka Mitsuda, and colleagues published in Nature Plants indicates that binding of this transcription factor is additionally affected by nucleobases that influence DNA shape but are not directly contacted by BIL1/BZR1.

To commemorate LGBTQIA+ STEM Day this year, we reached out to faculty in institutional and national leadership roles to discuss their academic journeys, the importance of having queer role models and ways to better support LGQTBIA+ researchers.