wolf in the wild

Wolves infected with the T. gondii parasite take higher risks

  • Connor J. Meyer
  • Kira A. Cassidy
  • Douglas W. Smith
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  • Dr. Nikki Traylor-Knowles is an Associate Professor of Marine Biology and Ecology at the University of Miami Rosenstiel School of Marine, Atmospheric, and Earth Science. Dr. Traylor-Knowles received her Ph.D. from Boston University and was a NSF Ocean Sciences postdoctoral fellow at Hopkins Marine Station before starting her own research lab in 2016. In this Q&A, Dr. Traylor-Knowles tells us about her work on understanding the complexities of coral and role as the founder of Black Women in Ecology, Evolution, and Marine Science (BWEEMS).

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  • Anti-retroviral therapy with drugs like dolutegravir is a powerful tool in both the treatment and prevention of HIV, but is limited by strict adherence to a daily therapeutic regimen. In a recent study, Deodhar, Sillman, and colleagues developed a dolutegravir prodrug that offers long-lasting protection against HIV infection, with the potential to dramatically improve anti-retroviral therapy efficacy.

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  • While recent advances in plant single-cell RNA sequencing (scRNA-seq) have made numerous strides in identifying novel regulatory events, transcriptional profiling of certain cell types, such as phloem poles, has not yet been thoroughly investigated. A recent article by Otero et al. utilized cell-type specific marker lines and a second-generation single-cell approach to uncover transcriptomic landscapes specifying protophloem-adjacent cells, as well as identify a set of important transcription factors (TFs) signifying early phloem development.

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A dividing cell in an early embryo

Cell cycle

One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated experimental approaches have rejuvenated the field. In addition, cell cycle regulators have emerged as cancer therapy targets. This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.
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