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  • Min Zheng

    Dr. Min Zheng is a principal investigator in Shenzhen Bay Laboratory in Shenzhen, China. His group is now focusing on the regulatory mechanisms of pathogen-induced inflammation and cell death (especially PANoptosis).

  • Effect of Kindlin alteration-induced mechanochemical alterations in the pancancer cohort.

    Debojyoti Chowdhury, Ayush Mistry and Shubhasis Haldar discuss their study on kindlin-associated global mechanochemical alterations in cancer.

  • Fig 1 from the paper

    Marco De Andrea and Stefano Raviola discuss their recent study showing how human cytomegalovirus infection triggers a paracrine senescence loop in renal epithelial cells.

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  • Documentation of women’s inclusion in Indian academia and conferences by BiasWatchIndia reveals the scale of underrepresentation of women across science, technology, engineering and mathematics.

    • Shruti Muralidhar
    • Vaishnavi Ananthanarayanan
    CommentOpen Access
  • Nanoparticle therapy continues to be an attractive avenue of targeted and personalised therapies. A molecular nano-conjugate developed by Zeng et al. effectively targets cancer cells and aids in their diagnosis, therapy, and also optimises innate immune responses.

    • Sharmistha Chatterjee
    Research HighlightOpen Access
  • Despite ample investigation on cis-regulatory alterations in evolution, the contribution of these effects to environmental adaptation is poorly understood. Ballinger and colleagues dissected the cis- and trans-regulatory impact on gene expression associated with the adaptation of house mice to temperate and tropical climates, highlighting potential mechanisms acting at a short evolutionary timescale.

    • Christina Paliou
    Research HighlightOpen Access
  • The physical properties of the cells and proteins surrounding a tumor play a crucial role in determining the spread of the cancer. How they change cancer cells to suppress the immune response against them is an interesting question addressed in a recent study from Liu et al., which describes how increased stiffness of the tissue around the tumor decreases the amount of a protein—cyclic GMP-AMP synthase—in cancer cells, ultimately blocking the immune response to cancer.

    • Joel P. Joseph
    Research HighlightOpen Access
Creative image of embryonic stem cells, cellular therapy. 3d illustration

In vitro models of human development

This cross-journal collection curated by Editors of Nature Communications, Communications Biology and Scientific Reports is dedicated to primary research that showcases the use of in vitro models to widen our understanding about formation of the human body.
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