Drill male (Afi Mountain Wildlife Sanctuary, Nigeria) / James Higham

COVID-19 risk in primates

Latest Research

  • Article
    | Open Access

    Nirav Chhabra et al. characterize adult mice carrying a homozygous mutation in Pax6 that was identified in a patient with foveal hypoplasia. They find that the Pax6 point mutation has pleiotropic effects, including defects in the mouse retinal structures, loss of the optic nerve, changes in energy metabolism and circadian rhythms, and dysregulation of genes expressed in the pancreas.

    • Nirav Florian Chhabra
    • , Oana Veronica Amarie
    • , Moya Wu
    • , Anna-Lena Amend
    • , Marina Rubey
    • , Daniel Gradinger
    • , Martin Irmler
    • , Johannes Beckers
    • , Birgit Rathkolb
    • , Eckhard Wolf
    • , Annette Feuchtinger
    • , Peter Huypens
    • , Raffaele Teperino
    • , Jan Rozman
    • , Gerhard K. H. Przemeck
    •  & Martin Hrabě de Angelis
  • Article
    | Open Access

    Ruhlandt et al. report a plasmonic nanocavity-based method to measure absolute values of quantum yield of commonly used fluorescent proteins. The method is calibration-free, does not require knowledge about maturation or potential dark states, and works on minute amounts of sample. Authors are further able to determine lifetime and quantum yield of several fluorescent proteins, which would be a good resource for researchers working with them.

    • Daja Ruhlandt
    • , Martin Andresen
    • , Nickels Jensen
    • , Ingo Gregor
    • , Stefan Jakobs
    • , Jörg Enderlein
    •  & Alexey I. Chizhik
  • Article
    | Open Access

    Joseph Korpela et al. demonstrate the use of machine-learning assisted bio-loggers on black-tailed gulls and streaked shearwaters. As video recording is only activated through variations in movement detected by low-cost accelerometers, this method represents improvements to runtime and precision over existing bio-logging technology.

    • Joseph Korpela
    • , Hirokazu Suzuki
    • , Sakiko Matsumoto
    • , Yuichi Mizutani
    • , Masaki Samejima
    • , Takuya Maekawa
    • , Junichi Nakai
    •  & Ken Yoda
  • Article
    | Open Access

    Lee et al. describe the generation of aglycosylated antibody-producing mice. These aglycosylated antibodies, lacking glycans prevent unwanted interactions with the lectins, and are used as reagents in a tool they developed called ALIQUAT. This aglycosylated antibody and lectin-based immunoassay diagnostic platform can be used to detect disease specific glycan biomarkers.

    • Nan-Ee Lee
    • , Sun Hee Kim
    • , Dae-Yeul Yu
    • , Eui-Jeon Woo
    • , Myung-Il Kim
    • , Gi-Sang Seong
    • , Sun Min Lee
    • , Jeong-Heon Ko
    •  & Yong-Sam Kim
  • Article
    | Open Access

    Zhang et al. characterize the functions of two distinct arginine kinase genes in flour beetles. Using RNA interference and electophoretic mobility shift assays, they identify Broad-Complex transcription factor as the mediator of opposing hormonal regulation in these genes.

    • Nan Zhang
    • , Heng Jiang
    • , Xiangkun Meng
    • , Kun Qian
    • , Yaping Liu
    • , Qisheng Song
    • , David Stanley
    • , Jincai Wu
    • , Yoonseong Park
    •  & Jianjun Wang
  • Article
    | Open Access

    Shi et al. use solid-state nuclear magnetic resonance spectroscopy to reveal the internal dynamics of human histones hH3 and hH4 in the Widom 601 and the telomeric nucleosome core particles. This work has implications for the propagation of epigenetic changes via the center of the nucleosome core communicating with histone tails and DNA.

    • Xiangyan Shi
    • , Chinmayi Prasanna
    • , Aghil Soman
    • , Konstantin Pervushin
    •  & Lars Nordenskiöld

News & Comment

  • Research Highlight
    | Open Access

    Aberrant cell signalling has been associated with a number of diseases. Belluati and coworkers make use of dual polymer nanocompartments encapsulating different enzymes, that function in unison as in a native signalling cascade. Their functionality is integrated into native cell metabolism and physiology, using substrates already present in the extracellular medium. They succeed in amplifying a natural signalling cascade and influencing cellular homoeostasis.

    • Anam Akhtar
  • Comment
    | Open Access

    Gillman and Wright propose a re-evaluation of taxonomical nomenclature to reinstate indigenous species names. These authors discuss the consideration of indigenous names for new and existing species in order to reflect the importance and precedence of indigenous knowledge in biology.

    • Len Norman Gillman
    •  & Shane Donald Wright
  • Research Highlight
    | Open Access

    Sabre-toothed carnivores are among the most famed vertebrate fossils in the world. The sabre-tooth ecomorph has been converged upon repeatedly by distantly related species throughout mammalian evolution. Lautenschlager et al. employ a range of biomechanical analyses to investigate the functional diversity of sabre-toothed skulls. Across 66 species, broad functional diversity is recovered with implications for prey specialization and niche partitioning, despite being morphologically convergent.

    • Luke R. Grinham
  • Q&A
    | Open Access

    João Conde began his independent career at NOVA Medical School of Universidade Nova de Lisboa in the beginning of 2020. In this short Q&A he tells us about his experience as an early career researcher, challenges he faced with science under lockdown, the advice he has for his younger self and what is the most likely science fiction vision we can achieve with nanotechnology.

  • Editorial
    | Open Access

    The metabolism of immune cells is a rapidly developing field with therapeutic implications. In recognition of this exciting area, our journal is welcoming submissions of primary research articles, perspectives, comments, and review articles in immunometabolism with the aim to highlight these articles in a special collection.

    • Shuai Jiang
  • Research Highlight
    | Open Access

    While polygyny is common among vertebrates, polygyny with mate fidelity has not yet been demonstrated in amphibians. A recent study by Fábio de Sá and colleagues shows that single male saxicolous frogs share a breeding territory with two females and mate multiple times with them over the course of a breeding season. These authors attribute the evolution of this mating system to the intense competition for territories and mates when access to these resources is scarce.

    • Caitlin Karniski

Collection

Editor's Picks in Genetics from Communications Biology

Hosoda et al. Commun. Biol. 3: 410 (2020), modified Fig 1.

Editor's Picks in Genetics from Communications Biology

In this collection, we celebrate the diversity of genetics and genomics research published this year in Communications Biology

Communications Biology