Human pancreatic islets

Single-cell imaging of α and β cell metabolic response to glucose in living human Langerhans islets

  • Fabio Azzarello
  • Luca Pesce
  • Francesco Cardarelli


  • drawing of graphs in black and white

    Communications Biology has a 2-year impact factor: 6.548 (2021), article downloads of 4,666,583 (2021) and 11 days from submission to the first editorial decision.

  • A fork in the road along a forest path.

    Learn more about the neural basis underlying how humans form beliefs in this post from Laura Müller-Pinzler, Alexander Schröder & Nora Czekalla.

  • Headshots of Kenro Kusumi and Sarah Gordon

    As part of our celebration of LGBTQIA+ STEM Day, we talked with Dr. Kenro Kusumi and Dr. Sarah Gordon about their research, leadership roles and advocacy for queer representation in STEM.

  • headshot of Bishal

    Our reviewer of the month is Dr. Bishal Paudel, a Postdoctoral Research Fellow in the Department of Biomedical Engineering at the University of Virginia. His interests lie in using multi-disciplinary approaches to understand the cellular/molecular basis of heterogeneity in cancer, and how that contributes to tumorigenesis and/or drug-resistance.


  • Dr. Nikki Traylor-Knowles is an Associate Professor of Marine Biology and Ecology at the University of Miami Rosenstiel School of Marine, Atmospheric, and Earth Science. Dr. Traylor-Knowles received her Ph.D. from Boston University and was a NSF Ocean Sciences postdoctoral fellow at Hopkins Marine Station before starting her own research lab in 2016. In this Q&A, Dr. Traylor-Knowles tells us about her work on understanding the complexities of coral and role as the founder of Black Women in Ecology, Evolution, and Marine Science (BWEEMS).

    Q&A Open Access
  • Anti-retroviral therapy with drugs like dolutegravir is a powerful tool in both the treatment and prevention of HIV, but is limited by strict adherence to a daily therapeutic regimen. In a recent study, Deodhar, Sillman, and colleagues developed a dolutegravir prodrug that offers long-lasting protection against HIV infection, with the potential to dramatically improve anti-retroviral therapy efficacy.

    • Angelo Mandarino
    Research Highlight Open Access
  • While recent advances in plant single-cell RNA sequencing (scRNA-seq) have made numerous strides in identifying novel regulatory events, transcriptional profiling of certain cell types, such as phloem poles, has not yet been thoroughly investigated. A recent article by Otero et al. utilized cell-type specific marker lines and a second-generation single-cell approach to uncover transcriptomic landscapes specifying protophloem-adjacent cells, as well as identify a set of important transcription factors (TFs) signifying early phloem development.

    • Jinbao Liu
    • Aqsa Majeed
    • M. Shahid Mukhtar
    Research Highlight Open Access
  • The viruses infecting bacteria, known as phages, carry a wondrous diversity of enzymes known as endolysins, which are responsible for opening cellular doors, like the membrane or wall, so that newly minted phages are set free. In a recent study, Oechslin and colleagues explored the evolutionary mystery of lactococcal endolysin biodiversity, suggesting that these endolysins are flexible and can be used as kinds of skeleton keys to open a broad range of cellular doors.

    • Melissa Walker
    Research Highlight Open Access
A dividing cell in an early embryo

Cell cycle

One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated experimental approaches have rejuvenated the field. In addition, cell cycle regulators have emerged as cancer therapy targets. This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.


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