Wake downstream of the SeaGen structure in Northern Ireland / Alex Nimmo-Smith

Localised anthropogenic wake generates a foraging hotspot

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  • Article | | open

    Cristina Zibetti et al. present ATAC-seq, RNA-seq and ChIP-seq analyses of murine retinal progenitors at early and late developmental stages. They find a central role for the LIM homeodomain transcription factor LHX2 in the global control of chromatin accessibility and identify Lhx2-dependent candidate pioneer factors that may contribute to the establishment and maintenance of open chromatin in the retina.

    • Cristina Zibetti
    • , Sheng Liu
    • , Jun Wan
    • , Jiang Qian
    •  & Seth Blackshaw
  • Article | | open

    Holly Vincent et al. use species distribution modeling, climate change projections, and geographical analyses of more than 1200 crop wild relatives, identifying 150 key conservation areas most effective in preserving genetic diversity of crop wild relatives.

    • Holly Vincent
    • , Ahmed Amri
    • , Nora P. Castañeda-Álvarez
    • , Hannes Dempewolf
    • , Ehsan Dulloo
    • , Luigi Guarino
    • , David Hole
    • , Chikelu Mba
    • , Alvaro Toledo
    •  & Nigel Maxted
  • Article | | open

    Jing Zhang et al. analyze glioblastoma patient data with a computational model integrating mutation-derived neoantigens similar to pathogen-specific antigens with enrichment of signatures for individual immune cells. Using a fitness model for identifying high-quality neoantigens and T lymphocyte infiltrates in glioblastoma, they uncover a subset of patients with prolonged survival.

    • Jing Zhang
    • , Francesca P. Caruso
    • , Jason K. Sa
    • , Sune Justesen
    • , Do-Hyun Nam
    • , Peter Sims
    • , Michele Ceccarelli
    • , Anna Lasorella
    •  & Antonio Iavarone
  • Article | | open

    Martin Brandt et al. studied foliage mass from Senegal over 30 years, observing the effects of climate change on dryland vegetation. Rainfall caused increases in both herbaceous and woody foliage, but woody vegetation benefits from rainfall timing changes with potential knock-on effects to the local herbivore populations.

    • Martin Brandt
    • , Pierre Hiernaux
    • , Kjeld Rasmussen
    • , Compton J. Tucker
    • , Jean-Pierre Wigneron
    • , Abdoul Aziz Diouf
    • , Stefanie M. Herrmann
    • , Wenmin Zhang
    • , Laurent Kergoat
    • , Cheikh Mbow
    • , Christin Abel
    • , Yves Auda
    •  & Rasmus Fensholt
  • Article | | open

    Josef Tkadlec et al. investigate population structures that mediate the trade-off between fixation probability and time. They identify structures that enable higher effective rates of evolution than the well-mixed population, which could be applied to in vitro evolution applications.

    • Josef Tkadlec
    • , Andreas Pavlogiannis
    • , Krishnendu Chatterjee
    •  & Martin A. Nowak
  • Q&A | | open

    Dr. Benjamin Bitler began his independent career at University of Colorado in January 2017. In this short Q&A he tells us about his motivation and passion for research, advice he would give to his younger self, and the attributes of cancer cells that he finds most perplexing.

  • Article | | open

    Gail Singer et al. demonstrate that cAMP waves are periodically initiated in the tip and propagate backward during multicellular Dictyostelium morphogenesis. This study suggests that propagating cAMP serves as the long-range intercellular communication signal beyond the initial aggregation process.

    • Gail Singer
    • , Tsuyoshi Araki
    •  & Cornelis J. Weijer


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