Focus
Inflammasomes
- Focus issue:
- April 2012 Volume 13, No 4
The inflammasome is associated with inflammation, and its dysregulation results in a variety of diseases ranging from cancer to autoimmunity. Nature Immunology presents five specially commissioned pieces on the activation, regulation and function of the inflammasome.
Editorial
Focus on The inflammasome
An inflammatory assemblage - p320
Zoltan Fehevari
doi:10.1038/ni.2268
Full Text - An inflammatory assemblage | PDF (209 KB) - An inflammatory assemblage
Overview
Focus on The inflammasome
Inflammasomes: far beyond inflammation - pp321 - 324
Jorge Henao-Mejia, Eran Elinav, Till Strowig & Richard A Flavell
doi:10.1038/ni.2257
Full Text - Inflammasomes: far beyond inflammation | PDF (206 KB) - Inflammasomes: far beyond inflammation
Reviews
Focus on The inflammasome
Sensing and reacting to microbes through the inflammasomes - pp325 - 332
Luigi Franchi, Raul Muñoz-Planillo & Gabriel Núñez
doi:10.1038/ni.2231
Full Text - Sensing and reacting to microbes through the inflammasomes | PDF (245 KB) - Sensing and reacting to microbes through the inflammasomes
Focus on The inflammasome
Regulation of inflammasome signaling - pp333 - 342
Vijay A K Rathinam, Sivapriya Kailasan Vanaja & Katherine A Fitzgerald
doi:10.1038/ni.2237
Abstract - Regulation of inflammasome signaling | Full Text - Regulation of inflammasome signaling | PDF (550 KB) - Regulation of inflammasome signaling
Focus on The inflammasome
Inflammasomes in carcinogenesis and anticancer immune responses - pp343 - 351
Laurence Zitvogel, Oliver Kepp, Lorenzo Galluzzi & Guido Kroemer
doi:10.1038/ni.2224
Abstract - Inflammasomes in carcinogenesis and anticancer immune responses | Full Text - Inflammasomes in carcinogenesis and anticancer immune responses | PDF (1,321 KB) - Inflammasomes in carcinogenesis and anticancer immune responses
Focus on The inflammasome
A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation? - pp709 - 714
Haitao Wen, Jenny P-Y Ting & Luke A J O'Neill
doi:10.1038/ni.2228
Abstract - A role for the NLRP3 inflammasome in metabolic diseases&emdash;did Warburg miss inflammation? | Full Text - A role for the NLRP3 inflammasome in metabolic diseases&emdash;did Warburg miss inflammation? | PDF (574 KB) - A role for the NLRP3 inflammasome in metabolic diseases&emdash;did Warburg miss inflammation?
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