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Focus
 
Antibody Engineering
  Contents     Editorial    News  Commentary
Feature Patents Reviews Feedback
This issue of Nature Biotechnology focuses on recent progress in antibody engineering and manufacture. Read on for reviews, news and commentaries on topics such as new types of antibody fragment, screening and selection strategies, clinical applications in oncology, immunoconjugates, intellectual property issues, manufacturing challenges, and the latest update on regulations. Art Credit: Jacques Deshaies "Deshaies 99". http://www.JacquesDeshaies.com
Editorial Top
Focus on Antibody Engineering and Manufacture
King in the kingdom of uncertainty p1025
doi:10.1038/nbt0905-1025
Full text | PDF (72K)
News Top
Focus on Antibody Engineering and Manufacture
Profile: Lisa Drakeman p1035
Laura DeFrancesco
Published online: 31 August 2005 | doi:10.1038/nbt0905-1035
Abstract | Full text | PDF (59K)
News Feature
Focus on Antibody Engineering and Manufacture
The problem with potency pp1037 - 1039
Christopher Thomas Scott
Published online: 31 August 2005 | doi:10.1038/nbt0905-1037
Abstract | Full text | PDF (131K)
Opinion and Comment Top
Commentary
Focus on Antibody Engineering and Manufacture
Empowering the inventor—the case of monoclonal antibodies pp1047 - 1049
Mike Clark
doi:10.1038/nbt0905-1047
Abstract | Full text | PDF (92K)
Focus on Antibody Engineering and Manufacture
Overhauling oversight—European drug legislation pp1050 - 1053
Lincoln Tsang
doi:10.1038/nbt0905-1050
Abstract | Full text | PDF (178K)
Focus on Antibody Engineering and Manufacture
Flexibility—the guiding principle for antibody manufacturing pp1054 - 1058
Keith L Carson
doi:10.1038/nbt0905-1054
Abstract | Full text | PDF (1,171K)
Features Top
Focus on Antibody Engineering and Manufacture
Upping the ante on antibodies pp1065 - 1072
Monya Baker
doi:10.1038/nbt0905-1065
Abstract | Full text | PDF (198K)
Focus on Antibody Engineering and Manufacture
Monoclonal antibody successes in the clinic pp1073 - 1078
Janice M Reichert, Clark J Rosensweig, Laura B Faden & Matthew C Dewitz
doi:10.1038/nbt0905-1073
Abstract | Full text | PDF (276K)
Patents
Focus on Antibody Engineering and Manufacture
The patentability of antibodies in the United States pp1079 - 1080
Deborah L Lu, Angela M Collison & Thomas J Kowalski
doi:10.1038/nbt0905-1079
Abstract | Full text | PDF (44K)
Focus on Antibody Engineering and Manufacture
Recent patent applications related to antibodies p1081
doi:10.1038/nbt0905-1081
Full text | PDF (29K)
Research Top
Reviews
Focus on Antibody Engineering and Manufacture
Selecting and screening recombinant antibody libraries pp1105 - 1116
Hennie R Hoogenboom
Published online: 07 September 2005 | doi:10.1038/nbt1126
Abstract | Full text | PDF (2,062K)
Focus on Antibody Engineering and Manufacture
Human antibodies from transgenic animals pp1117 - 1125
Nils Lonberg
Published online: 07 September 2005 | doi:10.1038/nbt1135
Abstract | Full text | PDF (3,019K)
Focus on Antibody Engineering and Manufacture
Engineered antibody fragments and the rise of single domains pp1126 - 1136
Philipp Holliger & Peter J Hudson
Published online: 07 September 2005 | doi:10.1038/nbt1142
Abstract | Full text | PDF (1,892K)
Focus on Antibody Engineering and Manufacture
Arming antibodies: prospects and challenges for immunoconjugates pp1137 - 1146
Anna M Wu & Peter D Senter
Published online: 07 September 2005 | doi:10.1038/nbt1141
Abstract | Full text | PDF (1,183K)
Focus on Antibody Engineering and Manufacture
Monoclonal antibody therapy of cancer pp1147 - 1157
Gregory P Adams & Louis M Weiner
Published online: 07 September 2005 | doi:10.1038/nbt1137
Abstract | Full text | PDF (4,999K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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