Nature Outline |

Liver cirrhosis

Long considered to be permanent, the extensive scarring found in livers with cirrhosis is now thought to be reversible. As understanding of scar formation grows, scientists are inching closer to treatments that will help to stop scarring and heal existing liver damage.

This Nature Outline is editorially independent. It is produced with third party financial support. About this content.

This Nature Outline is editorially independent, produced with financial support from a third party. About this content.


Once thought to be irreversible, cirrhosis of the liver now seems treatable — and drug development is proceeding apace.

Outline | | Nature

Many long-term diseases of the liver lead to scarring, or fibrosis, that restricts the organ’s functions. Evidence that fibrosis can regress has spurred the search for therapies that suppress scar-tissue formation to restore liver health.

Outline | | Nature