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Alzheimer disease

Alzheimer disease (AD) is a devastating neurodegenerative disorder that eventually results in dementia. Currently, there are no disease-modifying therapies for AD and the few available symptomatic treatments are of limited benefit. Thus, there is a pressing need to better understand this disease in order to develop effective treatments and to detect the disease in individuals before they exhibit extensive brain atrophy. This article series examines our current understanding of the pathophysiology of AD and some of the approaches being used to study this disease.

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