As the field of nephrology moves towards personalized medicine, knowledge and understanding of the genetic basis of renal disease is becoming increasingly important to inform patient care. In addition to genetic forms of renal disease, genetic variants and epigenetic regulators have a role in determining kidney function and development, the risk of, severity and progression of kidney disease, and responses to therapy. Genetic and genomic studies provide important insights into the mechanistic basis of kidney disease and have the potential to identify novel therapeutic targets. This series of articles aims to explore all aspects of nephrogenetics, from the genetics of monogenic diseases to complex traits and the interpretation and application of genetic and genomic data to improve patient outcomes.

Genetics of kidney disease

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