Supplements

Cardiovascular disease

Vol. 451, No. 7181 pp 903–957

In this supplement

• Editorial
• Reviews
• Progress

Cardiovascular disease is the most common cause of death worldwide and will become even more prevalent as the population ages. New therapeutic targets are being identified as a result of emerging insights into disease mechanisms, and new strategies are also being tested, possibly leading to new treatment options. Improving diagnosis is also crucial, because by detecting disease early, the focus could be shifted from treatment to prevention.

Editorial

Cardiovascular disease

Michael Basson

doi:10.1038/451903a

Full Text | PDF (100KB)

Reviews

Translating molecular discoveries into new therapies for atherosclerosis

Daniel J. Rader & Alan Daugherty

doi:10.1038/nature06796

Abstract | Full Text | PDF (1,912KB)

Triggers, targets and treatments for thrombosis

Nigel Mackman

doi:10.1038/nature06797

Abstract | Full Text | PDF (1,104KB)

Tackling heart failure in the twenty-first century

James O. Mudd & David A. Kass

doi:10.1038/nature06798

Abstract | Full Text | PDF (1,173KB)

A genetic framework for improving arrhythmia therapy

Björn C. Knollmann & Dan M. Roden

doi:10.1038/nature06799

Abstract | Full Text | PDF (673KB)

Stem-cell therapy for cardiac disease

Vincent F. M. Segers & Richard T. Lee

doi:10.1038/nature06800

Abstract | Full Text | PDF (2,410KB)

The developmental genetics of congenital heart disease

Benoit G. Bruneau

doi:10.1038/nature06801

Abstract | Full Text | PDF (329KB)

Progress

The search for new cardiovascular biomarkers

Robert E. Gerszten & Thomas J. Wang

doi:10.1038/nature06802

Abstract | Full Text | PDF (217KB)

Imaging of atherosclerotic cardiovascular disease

Javier Sanz & Zahi A. Fayad

doi:10.1038/nature06803

Abstract | Full Text | PDF (2,567KB)