Collection |

Cancer diagnostics

Advances in the isolation of cancer biomarkers in blood and in imaging probes will make a difference in the early detection of cancer.

This Collection is updated when relevant new content is published. Content appears in reverse chronological order. See all Collections from Nature Biomedical Engineering.

Research

The characterization of protein–protein interactions by combined single-molecule pull-down and single-molecule co-immunoprecipitation assays uncovers, for specific cancers, their dependence on signalling complexes of the human epidermal growth-factor receptor.

Article | | Nature Biomedical Engineering

News & Comment

An inexpensive assay that uses thermophoresis to concentrate cancer extracellular vesicles bound to aptamers specific for target proteins on the vesicles’ surface, can classify cancer patients according to cancer type and stage.

News & Views | | Nature Biomedical Engineering

A scalable and fast method for profiling single-molecule protein–protein interactions predicts the sensitivity of cells to inhibitors of the epidermal growth factor receptor, which is typically overexpressed in cancer.

News & Views | | Nature Biomedical Engineering