Focus
Focus on Natural Killer Cells
- Focus issue:
- May 2008 Volume 9, No 5
Five specially commissioned articles focus on the differentiation, responsiveness and biological roles of natural killer cells. The focus is available free to registrants for six months.
Editorial
Focus on Natural Killer Cells
Outside the box - p471
doi:10.1038/ni0508-471
This Focus on natural killer cells aims to highlight what is currently known and what remains to be understood about these important innate immune cells.
Full Text - Outside the box | PDF (141 KB) - Outside the box
Overview
Focus on Natural Killer Cells
Natural killer cells: diversity in search of a niche - pp473 - 475
James P Di Santo
doi:10.1038/ni.f.201
Abstract - | Full Text - Natural killer cells: diversity in search of a niche | PDF (326 KB) - Natural killer cells: diversity in search of a niche
Essay
Focus on Natural Killer Cells
Natural killer cell recognition of missing self - pp477 - 480
Klas Kärre
doi:10.1038/ni0508-477
The idea that NK cells can distinguish aberrant cells by recognizing 'absence of the expected', rather than 'presence of the unexpected' emerged more than 25 years ago. Klas Kärre recapitulates how the idea took shape, and the first five years of experimental work to test its general predictions.
Full Text - Natural killer cell recognition of missing self | PDF (217 KB) - Natural killer cell recognition of missing self
Perspectives
Focus on Natural Killer Cells
Mistaken notions about natural killer cells - pp481 - 485
Wayne M Yokoyama
doi:10.1038/ni1583
Abstract - | Full Text - Mistaken notions about natural killer cells | PDF (291 KB) - Mistaken notions about natural killer cells
Focus on Natural Killer Cells
Natural killer cell–directed therapies: moving from unexpected results to successful strategies - pp486 - 494
Magali Terme, Evelyn Ullrich, Nicolas F Delahaye, Nathalie Chaput & Laurence Zitvogel
doi:10.1038/ni1580
Abstract - | Full Text - Natural killer cell–directed therapies: moving from unexpected results to successful strategies | PDF (419 KB) - Natural killer cell–directed therapies: moving from unexpected results to successful strategies
Reviews
Focus on Natural Killer Cells
Up on the tightrope: natural killer cell activation and inhibition - pp495 - 502
Lewis L Lanier
doi:10.1038/ni1581
Abstract - | Full Text - Up on the tightrope: natural killer cell activation and inhibition | PDF (682 KB) - Up on the tightrope: natural killer cell activation and inhibition | Supplementary information
Focus on Natural Killer Cells
Functions of natural killer cells - pp503 - 510
Eric Vivier, Elena Tomasello, Myriam Baratin, Thierry Walzer & Sophie Ugolini
doi:10.1038/ni1582
Abstract - | Full Text - Functions of natural killer cells | PDF (703 KB) - Functions of natural killer cells | Supplementary information
Research Highlights
Focus on Natural Killer Cells
Research Highlights - p511
doi:10.1038/ni0508-511
Full Text - Research Highlights | PDF (73 KB) - Research Highlights